
Arachidonic acid CAS 506-32-1



Factory Supply Arachidonic acid CAS 506-32-1 with Best Price
- Appearance: White powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Arachidonic acid Supplier & Manufacturer
Arachidonic acid: The Complete Guide
- Item 1: Basic Info of Arachidonic acid
- Item 2: What is Arachidonic acid?
- Item 3: Arachidonic acid Uses
- Item 4: The Manager has Something to Say
- Item 5: Application of Arachidonic acid
- Item 6: Preparation of Arachidonic acid
- Item 7: Quality Control of Arachidonic acid
- Item 8: Hot Sale Products
- Item 9: Get Arachidonic acid Quotation
Arachidonic acid for Sale
Basic Info of Arachidonic acid
Chemical Name: | Arachidonic acid |
Other Name: | ARA arachidonic acid; Arachidonic fatty acid; (5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid |
CAS: | 506-32-1 |
EINECS: | 208-033-4 |
Type: | Food additives; Pharmaceutical raw materials; Organic raw materials; Flavors and Fragrances; Plant Extracts |
Molecular Formula: | C20H32O2 |
Molecular Weight: | 304.47 |
Melting point | -49 °C (lit.) |
Boiling point | 169-171 °C/0.15 mmHg (lit.) |
density | 0.922 g/mL at 25 °C (lit.) |
refractive index | n20/D 1.4872(lit.) |
Fp | >230 °F |
storage temp. | 2-8°C |
solubility | ethanol: ≥10 mg/mL |
form | oil |
pka | 4.75±0.10(Predicted) |
color | colorless to light yellow |
Water Solubility | PRACTICALLY INSOLUBLE |
Solvent | Ethanol under argon |
Specific Activity | 200-240 Ci/mmol |
Concentration | 1 mCi/ml |
Stability: | Light Sensitive, Temperature Sensitive |
Brand Name: | Zhishang Chemical |
Provide: | Arachidonic acid MSDS; Arachidonic acid COA |
What is Arachidonic acid?
All-cis-5,8,11,14-eicosatetraenoic acid, namely arachidonic acid (ARA), contains four carbon-carbon double bonds and one carbon-oxygen double bond, and is the most important polyunsaturated fatty acids. Widely distributed in the animal kingdom, a small amount exists in a certain species of glycerides, and can also be found in glycerophospholipids. Linoleic acid is the main source of synthesis in the adult human body, which can basically meet the physiological needs of the human body for arachidonic acid. However, in the state of metabolic disorders such as tumors, due to the increased demand, food supplements meet some of the needs, so it belongs to the category of arachidonic acid. Semi-essential fatty acids. Cognitive, cardiovascular, immune, and metabolic health effects are involved, and can promote muscle repair and growth, and eliminate inflammatory states in the body.
High-purity arachidonic acid is the direct precursor for the synthesis of prostaglandin, thromboxane and leukotriene and other 20-carbon derivatives. These biologically active substances play a very important role in the human cardiovascular system and immune system.
Arachidonic acid is an unsaturated fatty acid referred to as AA, and its chemical name is 5, 8, 11, 14-glycartetraenoic acid (all-cis configuration). It exists in some organs of animals and human body, such as brain, liver, pancreas and adrenal gland, etc., and also exists on the cell membrane of platelets and blood vessel walls. The precursor, so it can present a variety of functions in the body. Arachidonic acid is an unsaturated fatty acid, and higher animals can only synthesize it from linoleic acid obtained from food, so it is an essential fatty acid. Arachidonic acid is an important polyunsaturated fatty acid in the omega-6 series, which plays an important role in maintaining the structure and function of cell membranes in the body. It not only exists as an extremely important structural lipid widely in mammalian tissues (especially nervous tissue) organs, but also is an important precursor for the synthesis of prostaglandins in humans, with a wide range of biological activities and important nutritional effects. It has been widely used in the fields of health food, cosmetics and medicine.
Arachidonic acid Uses
- Manage heart excitability
Recent studies have reported that arachidonic acid and also its metabolites such as LTC4 can turn on the cardiac G protein-coupled toxoline-like K+ network in a receptor-independent manner, as well as control cardiac excitation under physiological as well as pathological problems. - Participation in neuroendocrine
Arachidonic acid can promote the secretion of former pituitary, placenta as well as mast cells, and take part in the law of the secretion of numerous hormonal agents and also neuropeptides in different neuroendocrine cells, such as oxytocin, vasopressin, insulin as well as glucagon, etc. - The duty of promoting cell division
Arachidonic acid and its metabolites have the impact of promoting cellular division, as well as its metabolites have this result in smooth muscular tissue cells, fibroblasts, and also lymphocytes. - Hinder platelet gathering
Arachidonic acid and its metabolites can trigger vasodilation. Vascular endothelial cells are very closely related to arachidase, which can release vasodilator variables, loosen up vascular smooth muscular tissue and dilate capillary under particular excitement. Because of the above physical functions, arachidonic acid is extensively used in the fields of cosmetics, medication as well as food.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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If you want to buy arachidonic acid, pls contact us to get a free quote.
Application of Arachidonic acid
Because the desaturase activity in infants and young children is very low, even if enough linoleic acid is taken in, the amount of AA required for growth and development cannot be synthesized. The fetus obtains AA from the mother through the placenta and accumulates it, and then obtains AA from breast milk and diet after birth. AA deficiency in fetuses and infants may be caused by low levels of AA in maternal blood or limited diets during artificial feeding. In view of the fact that AA is an essential nutrient for early human development and has special effects on fetal and infant central nervous system and retinal neurodevelopment, AA is mainly used in nutritional supplements for pregnant women and formula foods for infants and young children. AA is a natural component of breast milk. Decades of research in countries around the world have found that the average composition of breast milk is relatively consistent across the world, and the content of AA is between 0.5% and 0.7%. It is abundant in breast milk and almost absent in cow’s milk.
In 1994, in the report “Fats, Oils and Human Nutrition” submitted by joint experts of the United Nations Food and Oil Organization and the World Health Organization, new dietary guidelines were proposed, and it was recommended that infants and young children should consume AA through diet, and the recommended amount was “full-term”. 40mg per kilogram of body weight per day for infants and 60mg per kilogram per day for premature infants”. Since then, governments have successively approved AA as a nutritional fortifier to be added to baby food. In 1999, my country’s Ministry of Health officially recognized AA as a new type of nutritional fortifier. By the end of 2001, nearly 100 countries had approved the addition of AA to infant and young children’s food. In nutritional supplements for pregnant women, experts suggest adding a certain proportion of AA in addition to DHA (docosahexaenoic acid). The content in maternal blood and milk can not only bring good brain and optic nerve development to the fetus, but also reduce the incidence of prenatal eclampsia and postpartum depression in pregnant women, and also has a good regulatory effect on patients with gestational diabetes.
Because AA and its metabolites have strong biological activity in the human body, AA can be used as a functional active factor to make functional foods suitable for different groups of people or oral liquids suitable for special groups. Experts believe that it will become a functional food development. new growth point. AA has the functions of lowering blood sugar, blood lipids, preventing cardiovascular diseases, improving immunity, and increasing blood vessel elasticity. AA metabolites can also be used to relieve nervous tension, regulate central nervous system function, and play an important role in the prevention and treatment of cardiovascular and cerebrovascular diseases. , such as prostaglandins, leukotrienes, thromboxane. AA is the main essential fatty acid, which is closely related to lipid metabolism and is also important for cholesterol metabolism. Not only does it not cause hyperlipidemia and obesity like saturated fatty acids, on the contrary, it helps cholesterol transport and metabolism, preventing cholesterol deposition in the blood vessel wall and developing into atherosclerosis, which in turn plays a role in preventing hypertension and coronary heart disease. , myocardial infarction, cerebrovascular disease and other diseases prevention. Therefore, AA as a functional food has broad application prospects and great commercial value
In the past 20 years, the requirement of essential fatty acids in fish has been extensively studied at home and abroad. It is generally believed that the demand for arachidonic acid in fish is slow and can be met by the arachidonic acid contained in the feed (fish meat and fish oil), however, at a particular stage of the fish life cycle, high levels may be required. Arachidonic acid to adapt to the environment. AA is beneficial to fish growth, survival and resistance to stress; promote fish reproduction, improve the quality of eggs, sperm and seedlings; regulate fish immune function. Therefore, AA-rich fish feeds have broad market prospects.
In addition to being widely used in health food, AA is also widely used in cosmetics. AA is similar in function to γ-linolenic acid, but the skin care effect of AA is better than that of γ-linolenic acid; AA can replace or partially replace γ-linolenic acid to produce high-end skin care cosmetics; AA also has the functions of nourishing hair follicles and promoting hair regeneration , so it can also be used to develop hair care products, which can prevent and treat hair loss. Similar products have come out abroad. For example, Japan’s Shiseido has added AA to cosmetics to make skin care, hair care, anti-wrinkle and other beauty products to protect skin moisture. , delaying skin aging and treating chronic eczema. AA has a wide range of applications in the medical field. More than 90% of high-purity AA is very effective in treating hypertension, preventing pregnancy, induced abortion, relieving bronchial asthma, nasal congestion, and digestive system ulcers.
Preparation of Arachidonic acid
The traditional sources of arachidonic acid are animal liver, pig adrenal gland, blood, fish oil and egg yolk. But the content of AA in animal tissue is very low, about 0.2%, and limited by the source and season, the AA prepared by this method is expensive and cannot meet the needs of the market.
Compared with traditional preparation methods, the preparation of arachidonic acid by microbial fermentation has great advantages:
- The production cycle is short and the fecundity is strong.
- Not affected by climate, site, season and resources.
- There are many types of bacteria that can be used, and there is a lot of room for production improvement.
- The oil composition is closer to breast milk.
Since the 1970s, the production of arachidonic acid by fermentation has been carried out abroad. Fermented products of arachidonic acid are now on the market in the UK, Canada, the US and Japan. Domestic and foreign data show that the production of arachidonic acid by microbial fermentation was first discovered in 1979 when Penicillium cyaneu bacteria were rich in arachidonic acid. Although my country started late in this field, compared with foreign countries, it has certain advantages in the cultivation and selection of strains containing arachidonic acid.
Zhou Pengpeng and Yu Longjiang from the School of Life Science and Technology, Huazhong University of Science and Technology, obtained high-yielding strains such as Mortierella alpine T105 and Mortierella alpine M20 by mutagenizing the original arachidonic acid-producing strains, which were used for the production of arachidonic acid by microbial fermentation in my country. Acid research has made a huge contribution. Yao Jianming and Yu Inc. of the Center for Ion Beam Bioengineering, Institute of Plasma Physics, Chinese Academy of Sciences, and others used ion implantation to mutagenize the arachidonic acid-producing bacteria-Mortierella alpina N7, and obtained high-yielding strains I49-N18, which are the best in my country. Industrial microbial fermentation has laid a solid foundation for the production of arachidonic acid.
Reference
- Arachidonic acid – PubChem
- Yao Xin, Qin Wen, Qi Chunmei, et al. Physiological activity of arachidonic acid and its application[J]. Grain and Oil Processing and Food Machinery, 2004 (5): 57-59.
Arachidonic acid Supplier and Manufacturer
As a arachidonic acid supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best arachidonic acid raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for arachidonic acid and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
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* Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Arachidonic acid

