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Alpha-Cyclodextrin CAS 10016-20-3

10016-20-3
Alpha-Cyclodextrin
Alpha-Cyclodextrin
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  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: Alpha-Cyclodextrin Supplier & Manufacturer
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Alpha-Cyclodextrin: The Complete Guide

Alpha-Cyclodextrin for Sale

Basic Info

What is Alpha-Cyclodextrin?

Alpha-Cyclodextrin (Cyclodextrins, typically abbreviated as CD) are a course of D-glucopyranose systems linked end-to-end by alpha-1,4-glycosidic bonds created from starch or polysaccharides under the activity of cyclodextrin glucosyltransferase. The basic term for cyclic substances, common particles with 6, 7 and also 8 glucose units, are called α-cyclodextrin, β-cyclodextrin and also γ-cyclodextrin, respectively. Considering that α-cyclodextrin can develop inclusion complicateds with lots of visitor molecules, consequently transforming the physical and chemical residential or commercial properties of the visitor molecules such as solubility, stability, etc, it is extensively used in food, medicine, agriculture, fabrics, environmental management, cosmetics, biotechnology and evaluation Chemistry as well as other fields have a variety of applications.

Today, the cyclodextrin product produced in big quantities and also widely utilized in industry is β-cyclodextrin. Recently, α-cyclodextrin has gotten more and more focus because of its superb physical as well as chemical homes and also different features. Along with the qualities and also uses of other cyclodextrins, α-cyclodextrin is more suitable for incorporation of small molecules as a result of its inner dental caries dimension is smaller sized than that of β-cyclodextrin, as well as the application calls for cyclodextrin to have a higher solubility. High occasions. α-cyclodextrin is additionally made use of as a soluble dietary fiber or a material for improving metabolic disorder in the field of functional food and also pharmaceutical excipients. Its result of lowering blood sugar level focus and also weight-loss has actually likewise been authoritatively certified as well as acknowledged by the market.

Alpha-Cyclodextrin Uses

  • Change stomach feature and also improve irregularity
    Alpha-cyclodextrin will certainly be decomposed by some normal parasitic microorganisms in the intestine, as well as converted into a collection of short-chain fatty acids such as acetic acid, propionic acid, as well as butyric acid. These short-chain fats can inhibit the growth of damaging bacteria in the digestive tract, and also help the growth of probiotics such as bifidobacteria, and also the boost in the variety of probiotics in the human body can subsequently improve human resistance and also protect against enteritis, intestinal tract cancer, dysentery and constipation. α-cyclodextrin is commonly used in useful foods as food fiber or as an added material for improving metabolic syndrome.
  • Avoid and boost diabetes mellitus
    Alpha-cyclodextrin can protect against the absorption of carbs in the intestine, promote the excretion of encapsulated carbohydrates, minimize the peak blood sugar level after a high-starch dish, and achieve the result of inhibiting the increase of blood sugar level after a meal. α-cyclodextrin has a good impact on stopping as well as enhancing diabetic issues, as well as can be utilized as an efficient hypoglycemic health food raw material for people with hyperglycemia as well as kind diabetic issues to avoid postprandial hyperglycemia. EU Guideline No. 536 in 2013, in the declaration on food nourishment as well as wellness insurance claims, validated that alpha cyclodextrin has actually been medically confirmed to have the impact of controling blood sugar “Eating starchy dishes containing alpha cyclodextrin can decrease the increase in blood sugar level after meals Range”, if every 50 grams of starch consists of at the very least 5 grams of alpha cyclodextrin in the food that proclaims the quantity of a meal, the producer permits the tag on the bundle that the product has hypoglycemic result.
  • Boost the security of additives
    Alpha-cyclodextrin is used in combination with ingredients such as vitamin E, natural pigments (β-carotene, chlorophyll, etc), food tastes (such as rose oil, anethole, etc), which can enhance the security of the additives and help with long-lasting storage. Keep in food.

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This is William, CEO of Zhishang Chemical Co., Ltd.

Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.

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Alpha-Cyclodextrin and Blood Sugar

With the improvement of living standards, more and more high-glycemic index foods are on everyone’s table. After satisfying their appetite, people are increasingly troubled by metabolic diseases such as diabetes and insulin resistance.

The mechanism of these diseases may start with the rise of blood sugar after meals. High blood sugar directly stimulates the body to secrete too much insulin. If things go on like this, insulin resistance will gradually occur. In daily diet, if you can reduce postprandial blood sugar and insulin levels, you will better protect the body from related metabolic diseases.

Oral administration of α-cyclodextrin can reduce postprandial blood sugar and insulin levels, making blood sugar and insulin levels more stable, which is good news for healthy people, pre-diabetics and diabetics.

Alpha-cyclodextrin cannot be degraded by amylase, and can even directly inhibit the hydrolysis of amylose by combining with the active site of amylase, which makes α-cyclodextrin effective in inhibiting postprandial blood sugar fluctuations;

Higher doses of α-cyclodextrin intake can also increase satiety, slow gastric emptying, and help reduce sugar absorption, which is consistent with the effect of most dietary fibers.

At present, the European Food Safety Authority (EFSA) has confirmed that the addition of α-cyclodextrin can reduce the postprandial blood sugar rise of starch-containing meals, if the meal can ensure the intake of at least 5g of α- Cyclodextrin, the manufacturer can label the product as having hypoglycemic effect.

Alpha-Cyclodextrin and Blood Lipids

Over the past three decades, the number of obese patients has been increasing, and the number of obese people in my country has conservatively estimated to have exceeded 100 million. Excessive caloric intake, especially excessive dietary fat intake, is the chief culprit leading to obesity, and is also closely related to cardiovascular diseases such as atherosclerosis. Therefore, how to reduce dietary fat intake has become a hot topic of concern.

Oral administration of α-cyclodextrin can reduce dietary fat intake, lower blood cholesterol and triglyceride levels, increase adiponectin and leptin levels, improve plasma fatty acid distribution, and will not affect fat-soluble vitamins. Absorption makes an impact.

Alpha-cyclodextrin can form a stable complex with dietary fat in a high proportion, this complex cannot be hydrolyzed by digestive enzymes, and can be completely excreted from the human body through feces, thereby greatly reducing the bioavailability of fat;

Alpha-cyclodextrin can also reduce the micellar solubility of cholesterol by precipitating lecithin, thereby hindering the absorption of cholesterol in the lumen of the small intestine;

In addition, α-cyclodextrin can also selectively interfere with the absorption of inflammatory fats such as trans fats and saturated fats without affecting the absorption of polyunsaturated fats.

Reference

  1. α-Cyclodextrin – WikiPedia
  2. József Szejtli (1998). “Introduction and General Overview of Cyclodextrin Chemistry”. Chem.

Alpha-Cyclodextrin Supplier and Manufacturer

As a alpha-cyclodextrin supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best alpha-cyclodextrin raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for alpha-cyclodextrin and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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