(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone CAS 461432-22-4

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  • Appearance: White powder
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone Supplement

Basic Info of (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

What is (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone?

(5-Bromo-2-chlorophenyl) (4-ethoxyphenyl) ketone, also referred to as 5-bromo-2-chloro-4′-ethoxybenzophenone, is the key to the synthesis of dapagliflozin Intermediate. Dapagliflozin is a brand-new kind of anti-diabetic medicine collectively developed by Bristol-Myers Squibb and AstraZeneca. It is the initial SGLT2 prevention approved for the treatment of type 2 diabetic issues as a diabetes medicine therapy A crucial selection amongst grownups with type 2 diabetes as an adjunct to diet regimen as well as workout to improve glycemic control.

(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone Uses

(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone is an intermediate for improved synthesis of dapagliflozin, a novel selective type II Sodium-glucose co-transporter (SGLT2) inhibitor.

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Preparation of (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

Reference

  1. (5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone – PubChem
  2. [Chinese invention] CN201911337870.7 A kind of preparation method of 5-bromo-2-chloro-4′-ethoxybenzophenone

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