5-Aminolevulinic acid methyl ester hydrochloride CAS 79416-27-6

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  • Appearance: White powder
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: 5-Aminolevulinic acid methyl ester hydrochloride Supplement
79416-27-6

Basic Info of 5-Aminolevulinic acid methyl ester hydrochloride

What is 5-Aminolevulinic acid methyl ester hydrochloride?

Hydrochloride of methyl 5-aminolevulinate. It is a prodrug metabolized to protoporphyrin IX, a photosensitizer made use of in photodynamic treatment of non melanoma skin cancer (consisting of basal cell carcinoma). Topical application will certainly lead to the buildup of protoporphyrin IX in the skin lesions where the cream has actually been applied.

Subsequent irradiation with red light will produce toxic singlet oxygen, destroy the cell membrane and kill tumor cells. It can be used as an antineoplastic agent, photosensitizer, prodrug and dermatological drug. It comes from 5-aminolevulinic acid.

5-Aminolevulinic acid methyl ester hydrochloride Uses

  1. δ- Methyl ala (mal) and 5-aminolevulinic acid (5-ALA) are commonly used in photosensitizer reagents of photodynamic therapy to treat acne vulgaris and hypertrophic scar.
  2. Methyl 5-aminolevulinate hydrochloride, the methyl ester of aminolevulinic acid (ALA), has been shown to be more lipophilic and to induce protoporphyrin IX (PpIX) production efficiently in cell culture.
  3. Methyl 5-aminolevulinate hydrochloride is an ester derivative and can be used as a pharmaceutical intermediate.

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