4-tert-Octylphenol CAS 140-66-9

Factory Supply 4-tert-Octylphenol CAS 140-66-9 with Best Price

  • Appearance: White powder
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: 4-tert-Octylphenol Supplier & Manufacturer

Basic Info

What is 4-tert-Octylphenol?

4-tert-Octylphenol is a potential environmental pollutant that has toxic and estrogenic effects on mammalian cells. It binds to estrogen receptors as well as applies estrogenic impacts in vitro. Studied the photolysis of 4-tert-octylphenol under 253.7 nm irradiation and also hydrogen peroxide in liquid remedy ( λ Exc=253.7 nm).

4-tert-Octylphenol (OP) is an endocrine interfering with chemical that can have hazardous effects on human health. A typical toxic waste that displays weak estrogenic results. 4-tert-octylphenol has been revealed to create damage to the male reproductive system of vertebrates.

High doses of several Alkylphenol (including 4-tert-octylphenol) can change estrogen effects, including sexual hormone levels, estrous cycle, reproductive results, neonatal sexual development, steroid hormone production damage and testicular atrophy.

4-tert-Octylphenol Uses

  • 4-tert-Octylphenol is widely utilized in the production of oil-soluble octylphenolic resins, surfactants, pharmaceuticals, pesticides, additives, adhesives, and also ink fixing representatives.
  • Teroctylphenol belongs to the phenol derivatives, which have significant acidity and can undergo acid-base neutralization reactions with common inorganic bases. It is commonly used as a surfactant and adhesive for polymer materials, and is often used in the production process of fine chemicals. In addition, this substance is also commonly used as an intermediate in organic synthesis and is often used in basic chemical application research.
  • 4-tert-Octylphenol (4t-OP) is utilized as an intermediate in the production process to create surfactants, synthetic rubber ingredients, or resins. 4t OP is likewise used to manufacture Alkylphenol ethoxylates. It generally exists in detergents, cleaning products, and emulsifiers, yet is much less frequently located in paints, individual care items, insecticides, paper, pulp, and also fabrics.

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Application of 4-tert-Octylphenol

p-T-octylphenol can induce the apoptosis of brain neural progenitor cells in spawn computer mice, and as an endocrine disruptor, this material can be used as an estrogen medicine. In the production of great chemicals, p-tert-octylphenol is extensively made use of in the manufacture of oil-soluble octylphenol-formaldehyde resins, surfactants, medications, pesticides, additives, adhesives, and also ink fixatives. In organic artificial chemistry, p-tertoctylphenol can undertake nucleophilic alternative reaction with alkyl iodides under alkaline conditions to obtain matching alkyl ether by-products.

In a dry response flask, p-tert-octylphenol (3.72 g, 17.5 mmol) was liquified in anhydrous pyridine (15 ml) under argon ambience. The mix was cooled down in an ice-water bathroom, as well as trifluoroacetic anhydride (6 mL, 35 mmol) was gradually added dropwise by means of syringe to the resulting response combination, and also the ice-water bath was gotten rid of. The blend was permitted to mix over night and also the resulting yellow solution was poured into a separatory channel including a 1:1 diethyl ether/water mixture (100 mL). After mixing, the yellow aqueous phase was separated and also the natural phase was cleaned with water (50 ml) and 5% v/v hydrochloric acid remedy (2 x 50 ml). All water washes were integrated and also the liquid service was drawn out with 50 mL diethyl ether, the natural layer was separated and also dried over Na2SO4. The liquid service was filteringed system and evaporated to dryness. The resulting deposit was dissolved in a 20% diethyl ether/n-hexane mixture, and also the resulting reaction blend was slowly filtered through a pad of silica gel and eluted with 200 mL of the same combined solvent. The resulting anemic filtrate was evaporated to dry skin to acquire the target item molecule.


  • 4-tert-Octylphenol – PubChem
  • Estrada, Leandro A.; et al Organic Letters (2011), 13(13), 3304-3307

4-tert-Octylphenol Supplier and Manufacturer

As a 4-tert-octylphenol supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 4-tert-octylphenol raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for 4-tert-octylphenol and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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