
2,6-Dimethylaniline CAS 87-62-7
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- Appearance: Yellow liquid
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: 2,6-Dimethylaniline Supplement



2,6-Dimethylaniline: The Complete Guide
- Item 1: Basic Info of 2,6-Dimethylaniline
- Item 2: What is 2,6-Dimethylaniline?
- Item 3: 2,6-Dimethylaniline Uses
- Item 4: The Manager has Something to Say
- Item 5: Preparation of 2,6-Dimethylaniline
- Item 6: Reference
- Item 7: Quality Control of 2,6-Dimethylaniline
- Item 8: Hot Sale Products
- Item 9: Get 2,6-Dimethylaniline Quotation
2,6-Dimethylaniline for Sale
Basic Info of 2,6-Dimethylaniline
Chemical Name: | 2,6-Dimethylaniline |
Other Name: | 2,6-Xylidine; 2-Amino-m-xylene; 2,6-Dimethylaniline Solution |
CAS: | 87-62-7 |
EINECS: | 201-758-7 |
Type: | Agrochemicals; Pharmaceutical raw materials; Organic raw materials |
Molecular Formula: | C8H11N |
Molecular Weight: | 121.18 |
Melting point | 10-12 °C(lit.) |
Boiling point | 216 °C |
density | 0.984 g/mL at 25 °C(lit.) |
vapor pressure | <0.01 mm Hg ( 20 °C) |
refractive index | n20/D 1.560(lit.) |
Fp | 196 °F |
storage temp. | Store below +30°C. |
solubility | 13g/l |
form | Liquid |
pka | 3.89(at 25℃) |
color | Clear yellow to red-brown |
PH | 12.5 (100g/l, H2O, 20℃) |
PH Range | 12.5 |
explosive limit | 1.3-6.9%(V) |
Water Solubility | 7.5 g/L (20 ºC) |
Brand Name: | Zhishang Chemical |
Provide: | 2,6-Dimethylaniline MSDS; 2,6-Dimethylaniline COA |
What is 2,6-Dimethylaniline?
2,6-Dimethylaniline is an organic substance with the chemical formula C 6 h 3 (CH 3) 2 NH 2. It is among numerous isomeric xylene amines. It is an anemic thick liquid. Derivatives of industrial importance are the anesthetics lidocaine, bupivacaine, mepivacaine and articaine.
Numerous xyleneamines are prepared by nitration of xylene and hydrogenation of nitroaromatic substances, however this technique is inefficient for this isomer. Instead, it is prepared by treating the appropriate xylenol with ammonia in the existence of oxide catalysts.
2,6-Dimethylaniline responds with solid oxidants counteract acid in exothermic reaction to form salt and also water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acyl halides. Mix with solid reducing agents (such as hydrides) may create flammable gaseous hydrogen.
2,6-Dimethylaniline Uses
- 2,6-Xylidine is used in drugs, dye intermediates and organic synthesis. It is also used in the production of antioxidants, agriculture, medicine, rubber chemicals and other target organic molecules.
- 2,6-Dimethylaniline is an intermediate of pesticides, medicines and veterinary drugs.
- In the pesticide industry, 2,6-dimethylaniline is used in the production of high-efficiency fungicides metalaxyl, furalaxyl, furaxyl, furaxyl, benalaxyl, antiviral alum and high-efficiency and low-toxic selective herbicide isobutachlor , Teridor (Methachlor) and Imidazolamide, etc.
- In the pharmaceutical industry, 2,6-dimethylaniline is used in the production of anesthetics such as lidocaine hydrochloride, bupivacaine hydrochloride, fencaine hydrochloride, tocalium, and Dujuansu.
- 2,6-Dimethylaniline is the raw material for the production of veterinary drug Jingsongling.
The Manager has Something to Say

This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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Preparation of 2,6-Dimethylaniline
Using m-xylene as resources, it is gotten by mixed acid nitration and also catalytic hydrogenation. The procedure is to cool down m-xylene to 0 ~ 5 ℃, add the cooled down combined acid (56.5% sulfuric acid, 28% nitric acid, 15.5% water) in batches, keep the temperature level at 17 ℃ ~ 25 ℃ for the first time, include 3h. Finished, the second time was added at 17-25 ° C in 2h, the final dropwise temperature was 25-30 ° C, the enhancement was finished within 1h, and after that mixed at 25-30 ° C for 30min, the nitrates were divided and also washed with water, and after that minimized pressure The crude item was obtained by distillation, the fraction at 78-85 ° C/666.5 Pa was distilled again, and also 2,6-dimethylnitrobenzene was acquired by cooling down and also condensation.
2,6-dimethylnitrobenzene is minimized, and iron powder and also hydrochloric acid are utilized for stepwise reduction in the past, and iron powder is slowly contributed to 2,6-dimethylnitrobenzene as well as water down hydrochloric acid remedy, and afterwards refluxed after including 30min, cooling, after that including sodium carbonate to neutralize, adding water for distillation to get an oily option, layering, and also drying the oily layer to acquire an item. Catalytic hydrogenation has been utilized to change iron powder decrease. In the visibility of a stimulant, 2,6-dimethylnitrobenzene goes through catalytic hydrogenation to obtain a crude product, which goes through post-treatment to get a product.
The products generated by this method are 2,6-dimethylaniline as well as 2,4-dimethylaniline, while the share of 2,6-dimethylaniline in the response procedure is tiny, which can not satisfy the manufacturing demands. The manufacturing of 2,6-dimethylaniline by o-toluidine alkylation has become the focal point.
Alkylation technique, that is, making use of o-toluidine and methanol as basic materials, in the presence of a stimulant, the reaction is performed under a certain stress.
In this reaction, in addition to the major item 2,6-dimethylaniline, there are several spin-offs, of which 2,3-dimethylaniline and 2,6-dimethylaniline have comparable frameworks, comparable physical buildings, and steaming factors. The distinction is tiny and also the splitting up is more difficult. Normally, the alkylated catalysts are first separated from other by-products such as o-toluidine as well as tricolidine to get 2,3-dimethylaniline and also 2,6-dimethylaniline with a web content of 98%. The combination of base aniline, the blend is the starting material (in which the content of 2,3-dimethylaniline is 18%) through precision fractionation, the variety of theoretical plates in the entire tower is greater than 80, and the two elements can be totally Isolated to provide 2,6-dimethylaniline.
Reference
- 2,6-Xylidine – WikiPedia
- 2,6-Dimethylaniline – PubChem
Quality Control of 2,6-Dimethylaniline

