2-Nitrotoluene CAS 88-72-2

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  • Appearance: Yellow liquid
  • Assay: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: 2-Nitrotoluene Supplement

Basic Info of 2-Nitrotoluene

What is 2-Nitrotoluene?

Ortho-nitrotoluene, also known as 2-nitrotoluene, 1-methyl-2-nitrobenzene, o-methylnitrobenzene, methyl-o-nitrobenzene, o-Hydroxytoluene, o-nitrobenzene, o-nitrotoluene . Slightly soluble in water (0.061 at 30°C), soluble in benzene, chloroform and petroleum ether, miscible with ethanol and ether. Evaporates with water vapor.

Due to the strong electron-withdrawing property of the nitro group, the methyl group is easily oxidized. According to the oxidation conditions, o-nitrobenzaldehyde or o-nitrobenzoic acid can be generated; when reduced under the action of a catalyst, o-toluidine can be generated, and continued nitration to generate 2,4 or 2,6 dinitrotoluene; can also be chlorinated to generate nitrobenzyl chloride; can also generate azo compounds. Oral LD50 of rats is 801 mg/kg. o-Nitrotoluene is mainly used as a dye raw material to prepare dyes such as 4-chloro-2-nitrotoluene, 6-chloro-2-nitrotoluene, o-toluidine, bi-o-toluidine and 2,6-dichlorobenzaldehyde Intermediate; 4-chloro-2-nitrotoluene is also a pharmaceutical raw material; o-toluidine is also a raw material for pesticides and fungicides and a fragrance raw material; preparation of 2,2′-dinitrobenzyl, o-nitrobenzyl bromide and bromohexyl alkane and other pharmaceutical raw materials; preparation of indole as a raw material for amino acids and plant growth regulators; preparation of dinitrotoluene as a raw material for gunpowder; o-toluidine can also be used as a vulcanization accelerator; preparation of o-nitrobenzoic acid as a pharmaceutical raw material.

2-Nitrotoluene Uses

  1. 2-Nitrotoluene can be used as an intermediate for dyes and pesticides, as well as in the production of coatings, plastics and medicines, etc.
  2. 2-Nitrotoluene is mainly used in the production of o-toluidine and bitoluidine, and is an important raw material for dyes, coatings, plastics and medicines. In the pharmaceutical industry, it is used for the production of nifedipine, tongining, imipramine hydrochloride, bromhexylamine hydrochloride, diclofenac sodium penicillin, etc.
  3. 2-Nitrotoluene is used in industries such as dyes, pharmaceuticals, pesticides and plastics.

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Application of 2-Nitrotoluene

2-Nitrotoluene can be used as a raw material to synthesize other compounds such as o-nitrobenzaldehyde, o-nitrobenzoic acid, and dinitrotoluene. Examples of its application are as follows:


  1. 2-Nitrotoluene – Wikipedia
  2. 2-Nitrotoluene – PubChem

Quality Control of 2-Nitrotoluene

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