2-Hydroxyethyl-n-octyl-sulde CAS 3547-33-9

2-Hydroxyethyl n-octyl sulfide is a new type of micro-toxic (nearly non-toxic) and efficient insect repellent, which can effectively repel mosquitoes, flies, reptiles, ants, bed bugs, etc. effect. China has not seen any reports on the synthesis of parabens.

Abroad mainly adopt the substitution reaction method, the reduction reaction method, the exchange reaction method and the addition reaction method to prepare the insect alcohol. Among them, the substitution reaction method is generally through nucleophilic substitution to prepare beaconol, but this method uses a lot of toxic solvents. The reduction reaction method mainly uses elemental bromine as the reducing agent, but the yield is very low. The exchange reaction method uses 2-alkyl hydroxyethyl n-octyl sulfide and ethylene oxide to prepare bevelol, and its raw material 2-alkyl hydroxyethyl n-octyl sulfide is difficult to obtain. The addition reaction method can be divided into two methods: 1-octene as raw material and n-octane mercaptan as raw material. Although the former is an atom-economic reaction, the source of raw material 1-octene is less, and the latter is easy to generate by-products.