2-Acetylbutyrolactone CAS 517-23-7
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- Appearance: Colorless liquid
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: 2-Acetylbutyrolactone Supplier & Manufacturer
2-Acetylbutyrolactone: The Complete Guide
- Item 1: Basic Info of 2-Acetylbutyrolactone
- Item 2: What is 2-Acetylbutyrolactone?
- Item 3: 2-Acetylbutyrolactone Uses
- Item 4: Preparation of 2-Acetylbutyrolactone
- Item 5: Reference
- Item 6: The Manager has Something to Say
- Item 7: Quality Control of 2-Acetylbutyrolactone
- Item 8: Hot Sale Products
- Item 9: Get 2-Acetylbutyrolactone Quotation
2-Acetylbutyrolactone for Sale
Basic Info of 2-Acetylbutyrolactone
Basic Info
Chemical Properties
Other Info
Basic Info
Chemical Name: | 2-Acetylbutyrolactone |
Other Name: | Alpa-acetyl-gama-butyl ester; 2-Acetyl-γ-butyrolactone |
CAS: | 517-23-7 |
EINECS: | 208-235-2 |
Type: | Pesticide; Pharmaceutical raw materials; Organic raw materials |
Molecular Formula: | C6H8O3 |
Molecular Weight: | 128.13 |
Chemical Properties
Melting point | <25 °C |
Boiling point | 107-108 °C5 mm Hg(lit.) |
density | 1.19 g/mL at 25 °C(lit.) |
refractive index | n20/D 1.459(lit.) |
Fp | >230 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | 200g/l |
form | Liquid |
pka | 12.00±0.20(Predicted) |
color | Clear |
Water Solubility | 310 g/L (20 ºC) |
Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. |
Other Info
Brand Name: | Zhishang Chemical |
Provide: | 2-Acetylbutyrolactone MSDS; 2-Acetylbutyrolactone COA |
What is 2-Acetylbutyrolactone?
Alpa-acetyl-gama-butyl ester, likewise called 2-acetyl-γ-butyrolactone, is a crucial natural chemical raw material, an intermediate for the preparation of chlorophyll, as well as can likewise be utilized in the pharmaceutical market to make anti-angina pectoris medications. The raw materials for the preparation of vitamin B1 can additionally be used to synthesize 3,4-disubstituted pyridine as well as 5-(β-hydroxyethyl)-4-methylthiazole, which are widely utilized.
2-Acetylbutyrolactone is an important intermediate in the synthesis of chemical and pharmaceutical products such as vitamin B, 3,4-substituted pyridine, 5- (2-hydroxyethyl) – 4-methylthiazole. In the presence of 2-Acetylbutyrolactone, tert butyl isocyanate reacts with dialkyl acetylene dicarboxylate to form dialkyl (E) -2-{(tert butyl amino) [2-oxo-4,5-dihydro-3 (2H) – furanyl] methyl}-2-maleate. In addition, 2-Acetylbutyrolactone reacted with thiosemicarbazone and 3- (2-bromo-acetyl) – chrome-2-one in absolute ethanol to produce 3-{2-[5-hydroxyl-4- (2-hydroxy-ethyl) – 3-methyl-pyrazol-1-yl]-thiazol-4-yl}-chrome-2-one in good yield. In addition, 2-Acetylbutyrolactone can also be used as the raw material for the synthesis of pilocarpine, which is the main drug for the treatment of narrow-angle and wide-angle glaucoma. In addition, the chemical can also be used as a fluorescent reagent for the quantitative spectrofluorimetric determination of primary amines, which has been proved to be as accurate and accurate as the official or other reported methods.
2-Acetylbutyrolactone Uses
- 2-Acetylbutyrolactone is an intermediate for the synthesis of 2,4-disubstituted pyridine. A fluorescent reagent for spectrofluorimetric determination of primary amine.
- 2-Acetylbutyrolactone was used to synthesize 3,4-disubstituted pyridine; 5- (b-hydroxyethyl) – 4-methylthiazole.
- 2-Acetylbutyrolactone is an important intermediate in the synthesis of vitamin B. It is also an intermediate for the synthesis of 3,4-disubstituted pyridine and 5-(β-hydroxyethyl)-4-methylthiazole.
- Fluorescence spectrometry
2-Acetylbutyrolactone itself has only slight fluorescence, but its derivatives show high UV fluorescence. Carbonyl group can easily react with amine to form Schiff base. It is for this reason that 2-Acetylbutyrolactone is often used to confirm the production of amines in organic synthesis. 2-Acetylbutyrolactone can also form fluorescent molecules with aromatic amines through the Japp Klingemann reaction. - Drug precursor
2-Acetylbutyrolactone is used as a precursor of many drugs, including santalene and α- Methylene- γ- Butyrolactone.
Preparation of 2-Acetylbutyrolactone
2-Acetylbutyrolactone can be prepared by the condensation reaction of acetate (such as ethyl acetate) and butyrolactone in alkaline solution.
2-Acetylbutyrolactone can also be prepared by reacting ethylene oxide with ethyl acetoacetate under alkaline conditions.
Reference
- 2-Acetylbutyrolactone – WikiPedia
- 2-Acetylbutyrolactone – PubChem
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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2-Acetylbutyrolactone Supplier and Manufacturer
As a 2-acetylbutyrolactone supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 2-acetylbutyrolactone raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
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FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
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1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of 2-Acetylbutyrolactone
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