2 2′-Azobis(2-methylpropionamidine) dihydrochloride CAS 2997-92-4

98% / 99% High Purity 2 2′-Azobis(2-methylpropionamidine) dihydrochloride CAS 2997-92-4

Appearance:POWDER
Proportion: Minimum 99.0%
Inventory: In stock
Sample: Free sample
Zhishang Chemical: Supplier and manufacturer of 2 2′-Azobis(2-methylpropionamidine) dihydrochloride CAS 2997-92-4

Description of 2 2′-Azobis(2-methylpropionamidine) dihydrochloride:

2 2′-Azobis(2-methylpropionamidine) dihydrochloride, CAS 2997-92-4 acts as a highly reliable, water-soluble azo initiator. It features a molecular mass of 271.19 and the formula C₈H₂₀Cl₂N₆. Physically, this substance presents as a white or slightly off-white granular powder that melts between 160°C and 177°C. When working in labs, you can easily dissolve it in water, alcohol variants (methanol/ethanol), and DMSO.

The Underlying Mechanism

As a heat-triggered free radical initiator, 2 2′-Azobis(2-methylpropionamidine) dihydrochloride breaks down when temperatures rise, generating carbon-centered radicals. These intermediates bind with dissolved oxygen to form reactive peroxyl radicals. This thermal decay follows a strict first-order kinetic pathway. For reference, its operational half-life hits roughly 175 hours when held at 37°C, but drops sharply to 10 hours at 56°C.

Core Laboratory & Industrial Uses

Antioxidant Profiling (ORAC & CAA):

Scientists rely on this compound to create a uniform, steady stream of peroxyl radicals. This makes it possible to calculate precise fluorescence decay via AUC (area-under-the-curve) tracking. It remains the gold standard radical source for CAA and ORAC testing methods.

Forced Degradation in Pharma:

Unlike AIBN or ACVA, which contain nitrile groups that risk forming cyanohydrins and triggering false-positive peaks with amine-based APIs, this molecule uses a nitrile-free amidine design. It simulates oxidative stress without introducing unwanted cyanide or isocyanic acid artifacts.

Water-Compatible Polymer Production:

If you are synthesizing hydrogels, water-soluble polymers, or advanced nanoparticles, you need a radical source that stays in the aqueous layer. Because AIBN is hydrophobic and drifts into the oil phase (causing uneven chain growth), this water-friendly initiator ensures reaction control stays entirely within the water phase.

2 2′-Azobis(2-methylpropionamidine) dihydrochloride Chemical Properties

Melting point	175-177 °C(lit.)
density	0.42
vapor pressure	0Pa at 20℃
storage temp.	0-6°C
solubility	acetone, dioxane, methanol, ethanol, DMSO and water: soluble
form	granular
color	White to off-white
Water Solubility	176.2g/L at 20℃
Stability:	Unstable. Sensitive to heat and light. Incompatible with strong oxidizing agents, strong acids.
InChI	InChI=1S/C8H18N6.2ClH/c1-7(2,5(9)10)13-14-8(3,4)6(11)12;;/h1-4H3,(H3,9,10)(H3,11,12);2*1H/b14-13+;;
InChIKey	LXEKPEMOWBOYRF-QDBORUFSSA-N

2 2′-Azobis(2-methylpropionamidine) dihydrochloride 's supply advantage and supply capability

Uncompromising Quality Metrics

We deliver commercial batches with a minimum titration purity of 98%. Every order ships with a detailed Certificate of Analysis (COA) documenting actual melting points (typically 160-169°C), drying weight loss (capped under 1%), and appearance. This transparency ensures your polymerization runs and assays remain perfectly repeatable.

Warehouse Stocks Ready for Dispatch

We maintain a constant inventory buffer at our central fulfillment hub. While our standard catalog packs include 25g, 100g, 250g, and 500g bottles, we can customize containment options for your team. Small R&D quantities move out within 24 to 48 hours, while bulk commercial freight generally ships in 5 to 7 business days.

From Lab Benchs to Pilot Plants

We balance our operations to serve both independent research teams needing 25g for an initial ORAC test run and industrial plants requiring 20kg lots for manufacturing scale-ups. No matter where you sit on that spectrum, we can fulfill your volume requirements.

Deep Technical Expertise

Our in-house specialists know exactly how this initiator behaves across diverse chemical setups. Reach out if you need assistance troubleshooting its performance in oxidative stress testing, hydrogel crosslinking, or the polymerization of allyl, vinyl, and acrylamide monomers.

Safe Handling & Storage Logistics

Keep this product tightly sealed and stored in a temperature range of 0-40°C. It must remain isolated from direct heat sources, bright light, and oxidizing materials. Please note: this chemical is classified as a self-heating risk (Xn hazard rating, H302/H317 labels) and can ignite if exposed to excessive heat.

The packaging of 2 2′-Azobis(2-methylpropionamidine) dihydrochloride

We will use different standard packaging according to the product form.

● Liquid product: packaged in blue plastic drums, with a standard specification of 200 kg/drum; 220kg/barrel/250kg/barrel, tightly sealed barrel mouth, leak proof, resistant to bumps, suitable for long-distance transportation.

● Powdered products: packaged in thick cardboard drums, with a standard net weight of 25 kilograms per drum; 200 kg/barrel; 220kg/barrel/250kg/barrel, the barrel body is sturdy and pressure resistant, while also having good moisture resistance.

● Sample: sealed uniformly in aluminum foil bags with strong sealing abilities, which can prevent moisture and air from entering the bag and cause it to deteriorate.

Packaging can be tailored to meet customer needs, with standard packaging processes that ensure the quality of goods is maintained during storage and transport.

2 2′-Azobis(2-methylpropionamidine) dihydrochloride Supplier and Manufacturer

As a 2 2′-Azobis(2-methylpropionamidine) dihydrochloride supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 2 2′-Azobis(2-methylpropionamidine) dihydrochloride raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for 2 2′-Azobis(2-methylpropionamidine) dihydrochloride and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

Zhishang Chemical has its own R&D lab, with professional teams and advanced equipment. We also have rigorous processes and procedures to ensure the quality of our products.

▶ The laboratory is over 1500 square metres in size, and has been divided into functional zones to accommodate testing requirements.

▶ The core R&D Team consists of three PhDs and seven or more masters with rich technical expertise.

▶ Equipment with international advanced analytical and testing equipment, such as HPLC GC, FTIR NMR AAS etc. to achieve precise control during the entire process.

▶ We can develop customized products and will optimize formulas and processes according to customer needs.

▶ Set strict standards for product quality inspection and make sure that each batch is subjected to multiple inspection stages in order to ensure stable and reliable performance.

FAQ:

How do AAPH and AIBN differ in the lab?

It comes down to solubility and byproduct safety. AIBN requires organic solvents because it hates water, and its nitrile base can release dangerous cyanide artifacts during pharmaceutical stress testing. Our product dissolves cleanly in water and features an amidine structure, making it a safer option for API stability workflows.

What are the standard packaging configurations?

Our baseline purity stays at ≥98%. We ship standard quantities of 25g, 100g, 250g, and 500g. Bulk shipments are fully supported, and we can accommodate unique custom packing requests from your production team.

What is the proper way to handle storage?

Keep the container locked tight at 0-40°C in a dry environment. Protect the powder from moisture and light. Because it is a self-heating chemical, keep it far away from oxidizing reagents.

Why is this compound crucial for testing antioxidants?

It provides a completely predictable, controlled release of peroxyl radicals at a human body temperature of 37°C. This level of kinetic stability allows different labs around the world to achieve matching AUC data.

Can we negotiate wholesale or volume discounts?

Absolutely. We cater to long-term contract buyers in the pharmaceutical and polymer manufacturing sectors. While our minimum order starts at 25g, you can speak with our sales desk to establish custom volume pricing agreements.