1,2-Pentanediol CAS 5343-92-0

Factory Supply 1,2-Pentanediol CAS 5343-92-0 with Best Price

  • Appearance: Colorless liquid
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: 1,2-Pentanediol Supplier & Manufacturer

Basic Info

What is 1,2-Pentanediol?

1,2-Pentanediol is an important organic intermediate utilized in the synthesis of propiconazole, a special fungicide for industrial crops; it additionally has excellent hydrating residential or commercial properties as well as antibacterial impacts, and is utilized in skin lotions, eye creams, skin creams, and baby care. It is likewise an important raw material for the production of polyester fibers, surfactants, drugs and various other products.

1,2-Pentanediol is an outstanding humectant with anti-bacterial properties, as well as its synergistic impact with traditional chemicals likewise helps in reducing the quantity of typical chemicals in formulas. In sun block items, it is much more valuable to enhance the water resistance of the product and also the capacity to liquify some components. 1,2-Pentanediol helps to maintain formulas while also minimizing the sticky feel of solutions due to added polymers.

1,2-Pentanediol Uses

  1. Broad-spectrum anti-bacterial activity, can efficiently hinder Gram-negative microorganisms, favorable germs, yeast and mold and mildew.
  2. As an emollient, 1,2-pentanediol has great skin moisturizing homes, can reduce the loss of water in the skin, make the skin soft and also smooth, and enhance the emollient feature of skin treatment items.
  3. Pentylene glycol is a multi-functional ingredient with excellent inhibitory ability to microorganisms. Its ingredients are not registered as preservatives. It can be used in cosmetics and fully supports the concept of “zero added preservatives”.
  4. Mild and non-irritating, reducing the irritation and allergy caused by preservatives, it is a high-purity liquid emollient with broad-spectrum antibacterial effect, classified as emollient, very mild, in line with international regulatory trends, and widely used around the world.
  5. 1,2-Pentanediol has good compatibility and can be added to the oil phase to improve the water resistance of sunscreen product formulations; it is soluble in water and easily soluble in polyols such as ethylene glycol, propylene glycol, and glycerin.

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Application of 1,2-Pentanediol

1,2-O-diol is an important chemical raw material, which is often used to produce polyester, surfactant, and can also be used as a raw material for pharmaceuticals. Linear 1,2-vicinal diols, especially C2-C4 vicinal diols, are mostly prepared by hydration of epoxides at high temperature and pressure or under alkaline or acidic conditions, and can also be prepared by oxidative hydration of terminal olefins.

1,2-Pentanediol (1,2-o-diol of C5) is an important organic intermediate. It is mainly used for the synthesis of bactericide propiconazole, and is also used in the production of polyester fibers, surfactants, cosmetics, and pharmaceuticals. important raw materials for other products. US Patent US4605795A (1986-08-12) discloses a continuous production process in which n-pentene and peroxypropionic acid are reacted in a solvent to generate 1,2-epoxypentane, which is then rehydrated to obtain 1,2-pentanediol.

1,2-Pentanediol is a straight-chain diol with distinct polar and non-polar ends, which is different from other diols in nature and has versatility. It is the key intermediate of the systemic fungicide propiconazole with high efficiency, low toxicity and long lasting effect; propiconazole has played an important role in the prevention and control of fungal diseases such as food crops, vegetables and fruits, and has a very broad application prospect. . As an excellent moisturizing agent, antibacterial agent and solubilizer, 1,2-pentanediol can effectively improve the water resistance of sunscreen cosmetics, and is widely used in various daily care products.

In addition, 1,2-pentanediol is also an important raw material for products such as polyester fibers, surfactants and pharmaceuticals. Existing literature reports that the technique of synthesizing 1,2-pentanediol mainly contains 2 kinds: a kind of takes n-valeric acid as raw material, obtains alpha-bromo-n-valeric acid through bromination, obtains alpha-hydroxyvaleric acid through hydrolysis, adds After hydrogen reduction, 1,2-pentanediol is obtained. The other uses n-pentene as raw material, adopts formic acid/hydrogen peroxide or peroxypropionic acid and other oxidant systems to oxidize n-pentene to pentane oxide; hydrolyze under alkaline conditions to obtain 1,2-pentanediol . The above-mentioned 1,2-pentanediol synthesis route adopts the petrochemical product C5.

The C5 fraction produced in the petrochemical industry is generally used as fuel, and the yield of 1-pentene or other deep-processed products that can be used as raw materials after rectification and separation is very low, resulting in high raw material cost for producing 1,2-pentanediol. The prior art adopts multi-step reaction, and there are many types of by-products, resulting in low yield and product purity of 1,2-pentanediol, and high price; backward production technology is also an important reason affecting the development of 1,2-pentanediol, which is extremely It greatly limits the industrial production of 1,2-pentanediol.

Preparation of 1,2-Pentanediol

150g Hydrogenation catalyst-alloy catalyst (composed of 60g copper oxide, 45g zinc oxide and 45g aluminum oxide) was packed in the hydrogenation reactor, the temperature in the reactor was maintained at 165°C, and the hydrogen pressure was maintained at 14MPa, and the hydrogenation was carried out from the lower end. Reactor, the 2-hydroxyvalerate methyl ester that produces in the above-mentioned reaction enters hydrogenation reactor from lower end, the feed flow rate of 2-hydroxyvalerate methyl ester (171g) is controlled at 2ml/min, and the product of hydrogenation reaction is from hydrogenation reaction. The top of the device flows out, and the effluent is cooled to 60 ° C through the condenser, transferred to the distillation still, and the distillation temperature is 160 ° C to obtain 121.6 g of 1,2-pentanediol, and the 1,2-pentanediol prepared above is detected by gas chromatography. The 1,2-pentanediol content was 99.3%, and the molar yield was 90.26%.


  • 1,2-Pentanediol – PubChem
  • Luo Yan, Xu Baoming, Tang Guoliang, & Chen Kun. (2010). Progress in the synthesis of propiconazole intermediate 1,2-pentanediol. Pesticides, 49(3), 161-163.

1,2-Pentanediol Supplier and Manufacturer

As a 1,2-pentanediol supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 1,2-pentanediol raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for 1,2-pentanediol and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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