1,2-Pentanediol CAS 5343-92-0

1,2-O-diol is an important chemical raw material, which is often used to produce polyester, surfactant, and can also be used as a raw material for pharmaceuticals. Linear 1,2-vicinal diols, especially C2-C4 vicinal diols, are mostly prepared by hydration of epoxides at high temperature and pressure or under alkaline or acidic conditions, and can also be prepared by oxidative hydration of terminal olefins.

1,2-Pentanediol (1,2-o-diol of C5) is an important organic intermediate. It is mainly used for the synthesis of bactericide propiconazole, and is also used in the production of polyester fibers, surfactants, cosmetics, and pharmaceuticals. important raw materials for other products. US Patent US4605795A (1986-08-12) discloses a continuous production process in which n-pentene and peroxypropionic acid are reacted in a solvent to generate 1,2-epoxypentane, which is then rehydrated to obtain 1,2-pentanediol.

1,2-Pentanediol is a straight-chain diol with distinct polar and non-polar ends, which is different from other diols in nature and has versatility. It is the key intermediate of the systemic fungicide propiconazole with high efficiency, low toxicity and long lasting effect; propiconazole has played an important role in the prevention and control of fungal diseases such as food crops, vegetables and fruits, and has a very broad application prospect. . As an excellent moisturizing agent, antibacterial agent and solubilizer, 1,2-pentanediol can effectively improve the water resistance of sunscreen cosmetics, and is widely used in various daily care products.

In addition, 1,2-pentanediol is also an important raw material for products such as polyester fibers, surfactants and pharmaceuticals. Existing literature reports that the technique of synthesizing 1,2-pentanediol mainly contains 2 kinds: a kind of takes n-valeric acid as raw material, obtains alpha-bromo-n-valeric acid through bromination, obtains alpha-hydroxyvaleric acid through hydrolysis, adds After hydrogen reduction, 1,2-pentanediol is obtained. The other uses n-pentene as raw material, adopts formic acid/hydrogen peroxide or peroxypropionic acid and other oxidant systems to oxidize n-pentene to pentane oxide; hydrolyze under alkaline conditions to obtain 1,2-pentanediol . The above-mentioned 1,2-pentanediol synthesis route adopts the petrochemical product C5.

The C5 fraction produced in the petrochemical industry is generally used as fuel, and the yield of 1-pentene or other deep-processed products that can be used as raw materials after rectification and separation is very low, resulting in high raw material cost for producing 1,2-pentanediol. The prior art adopts multi-step reaction, and there are many types of by-products, resulting in low yield and product purity of 1,2-pentanediol, and high price; backward production technology is also an important reason affecting the development of 1,2-pentanediol, which is extremely It greatly limits the industrial production of 1,2-pentanediol.