1,1,1-Trifluoroacetone CAS 421-50-1

Factory Supply 1,1,1-Trifluoroacetone CAS 421-50-1 with Best Price

  • Appearance: Colorless liquid
  • Purity: 99. 0%min
  • Stock: In stock
  • Sample: Available
  • Zhishang Chemical: 1,1,1-Trifluoroacetone Supplier & Manufacturer

Basic Info

What is 1,1,1-Trifluoroacetone?

Trifluoroacetone (TEK) is a very useful fluorine-containing fine chemical and one of the most valuable products in fluorine-containing ketones. A variety of important fine chemical intermediates can be derived from trifluoroacetone, such as hydrogenation reduction to obtain trifluoropropanol; and aromatic compounds to generate tertiary alcohols; bromination in the presence of sulfuric acid to obtain universal synthetic building block tribromide Fluoroacetone, reacts with m-nitroaniline to generate photographic coupler, etc.

The reduction product trifluoropropanol is used as a solvent and catalyst in the synthesis of various polymers and fine chemicals, and is widely used in dyes, photosensitive materials, liquid crystal display materials, aerospace technology, pesticides, medicine, polymer materials and other fields. It is an important intermediate for the synthesis of biologically active substances and antihypertensive drugs, and has very good development and application prospects. Since the residue of fluorine-containing pesticides is small and does not pollute the environment, the dosage is increasing year by year. Therefore, the use of trifluoroacetone in the synthesis of fluorine-containing pesticides also has good social, economic and environmental benefits.

1,1,1-Trifluoroacetone Uses

  • An important intermediate for synthesizing bioactive substances and antihypertensive drugs, as well as a very useful organic synthetic block and trifluoromethylation reagent.
  • Used for the synthesis of 2-trifluoromethyl-7azaindole from 2,6-dihalopyridine. Derived chiral imines are used for preparing enantiomeric purity through Strecker reaction followed by nitrile hydrolysis or reduction α- Trifluoromethylalanine and diamine.
  • 1,1,1-trifluoroacetone is used as an intermediate of bioactive substances and antihypertensive drugs, as well as an effective synthetic block and trifluoromethyl reaction reagent.
  • 1,1,1-trifluoroacetone is a general chemical reagent used to synthesize glucokinase glucokinase regulatory protein (GK-GKRP) interferon, which can be a potential target for patients with type II diabetes. The reactant of an enantioselective Cycloaddition reaction.


  1. Trifluoroacetone – WikiPedia
  2. Prakash, G. K.Surya; Wang, Fang (2011). “1,1,1-Trifluoroacetone”. Encyclopedia of Reagents for Organic Synthesis

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1,1,1-Trifluoroacetone Supplier and Manufacturer

As a 1,1,1-trifluoroacetone supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 1,1,1-trifluoroacetone raw materials to customers all over the world.

Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.

If you have a demand for 1,1,1-trifluoroacetone and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.

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