S malic acid CAS no 97-67-6

S malic acid CAS no 97-67-6

The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.

Production methods

1. Microorganism (or enzyme) conversion of anti-butenic acid production of l-malate, short of yellow bacillus, and the production of short bacteria such as aminobacteria can convert fumaric acid into malic acid. First the raw material of fumaric acid react with calcium carbonate to produce fumaric acid calcium, then through conversion column (37 ℃), generate malic acid calcium, the L – malic acid, conversion rate can reach 98%.

2. The strains of a single step fermentation production of L – malic acid aspergillus oryzae, parasitic aspergillus, aspergillus Flavus and other microbes can sugar fermentation raw material to produce L – malic acid, with big MiTang as raw material, with yellow aspergillus (ASP Flavus UV

T3) in the 500L fermentation tank, ventilated and fermented 40h, the yield of acid was 4.4%~4.95%, and the conversion rate of sugar was 68%~75%.

use

L-malic acid is used in food, medicine, daily chemical industry and other industries as follows:

(1) food industry: it is used for the processing and distribution of beverages, dews and fruit juices, and also for the manufacture of confectionery, jam, etc., for food and antibacterial and preservative effect. It can also be used in the PH regulation of sour milk fermentation.

(2) tobacco industry: malic acid derivatives (such as ester) can improve the aroma of tobacco.

Product expansion

1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the Raw Material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories.

2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.

3> Fragrance And Spices: Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion.

6> Pharmaceutical Intermediates: The so-called pharmaceutical intermediates, refers to the production of pharmaceutical products in the process, the use of raw materials, materials, accessories and other intermediate products.

7> Agricultural Chemicals: Research and agriculture related chemical, including pesticide, plant growth regulator, fertilizer, compound fertilizer, herbicide etc.