Place of Origin:
Antihypertensive drugs; Cardiovascular and cerebrovascular drugs; Drugs; Cardiovascular and cerebrovascular diseases; Medical raw materials; Raw material intermediate – API; Small molecule inhibitors; Rare earth metals and compounds; API; Signal transduction pathway kinase inhibitors; Isotope; Pharmaceutical intermediates; Endocrine and hormone; Pharmaceutical raw materials; chemical compound; Antihypertensive drugs; Traditional Chinese medicine reference substance; Standard; Hypoglycemic and antihypertensive products; Other raw materials; Drug impurities and intermediates; Raw materials; Chemical raw materials; Medical raw materials; ActivePharmaceuticalIngredients; CaChemicalbookndesartanCilexetil; APIintermediates; Bases&RelatedReagents; Intermediates&FineChemicals; Nucleotides; Pharmaceuticals; CandesartanCilexatil; Aromatics; Heterocycles; Pharmaceuticalrawmaterial
Cool Dry Place
- Crystalline Solid
- Colorless crystals were obtained from ethyl acetate methanol, melting point 183 ~ 185 ℃. Candesartan cilexetil: c33h34nchemicalbook6o6. [145040-37-5]。 1 – [[(cyclohexyloxy) carbonyl] oxy] ethyl ester. Colorless crystal is obtained from ethanol water, melting point 163 ℃ (decomposition).
- An angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive
- antihypertensive, angiotensin II inhibitor
- Antihypertensive drugs. Angiotensin Ⅱ – 1 receptor antagonist. Ester is a precursor drug, which is hydrolyzed into acid in human body.
- Angiotensin II receptor antagonist for the treatment of hypertension
- Candesartan axetil was rapidly hydrolyzed into the metabolite candesartan in vivo. Candesartan is an angiotensin Ⅱ receptor (AT1) antagonist. By binding to AT1 receptor of vascular smooth muscle, chemical Book antagonizes the vasoconstriction of angiotensin Ⅱ, so as to reduce peripheral vascular resistance. It is also considered that candesartan can play a certain antihypertensive role by inhibiting the secretion of aldosterone by adrenal gland.
- Experiments in patients with hypertension showed that repeated administration of this product could increase plasma renin activity, angiotensin I concentration and angiotensin II concentration; Continuous administration of 2-8mg once a day can reduce systolic and diastolic blood pressure, chemical book, left ventricular myocardial weight and peripheral vascular resistance, but has no significant effect on cardiac output, ejection fraction, renal vascular resistance, renal blood flow and glomerular filtration rate; It has no effect on cerebral blood flow in patients with essential hypertension with cerebrovascular disorders.
The production base is located in Zhangqiu chemical industry park and Tai’an high-tech chemical industry park. laboratory and workshop in strict accordance with the GMP standard and the product fit national ISO9001 and ISO2000 standards.
“Zhishang” products are exported to Europe, North and South America, the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.
- Business Type: Manufacturer
- Product Range: Additive , Chemical Auxiliary & Catalyst , Organic Chemicals
- Products/Service: Organic Intermediate,Inorganic Chemistry, APIs, Dyestuffs And Pigments, Fragrance And Spices, Food Additives
- Total Employees: 51~100
- Capital (Million US $): 10000000RMB
- Year Established: 2016
- No. of Production Lines : 8
- No. of QC Staff : 5 -10 People
- OEM Services Provided : yes
- Factory Size (Sq.meters) : 3,000-5,000 square meters
- Certificate: ISO9001 , CE , GMP , API , MSDS
- Factory Location : Diao Town Industry Park, Zhangqiu City, Jinan City, Shandong Province, China.
* Prompt reply and 24 hours online, professional team to provide best price and high quality product.
* Sample testing support.
* Every batch of products will be tested to ensureits quality.
*The packing also can be according the customers` requirment.
*Any inquiries will be replied within 24 hours.
*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
*The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
*Product has any problem can return.
Do you accept sample order?
We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Is there a discount?
Different quantity has different discount.
1. ≤50kg, Express delivery recommended, usually called as DDU service;
2. ≤500kg, Air shipping recommended, usually called as FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called as FOB, CFR, or CIF service;
4. For high value products, please select air shipping and express delivery for safe.