N,N-Dimethylformamide CAS 68-12-2 DMF
Factory Supply N,N-Dimethylformamide CAS 68-12-2 DMF with Best Price
- Appearance: Colorless liquid
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: N,N-Dimethylformamide Suppliers & Manufacturers
N,N-Dimethylformamide: The Complete Guide
N,N-Dimethylformamide for Sale
N,N-dimethyl formamide; N,N-Dimethylformamide DMF
Pharmaceuticals, pesticides, dye intermediates; Agrochemicals; Organic raw materials
What is N,N-Dimethylformamide?
N,N-Dimethylformamide (abbreviated as DMF) is a colorless, transparent liquid with strong polarity and low toxicity, making it a good organic solvent. With the rise of biopharmaceuticals, N,N-dimethylformamide (DMF) has been widely used as a solvent in the preparation of APIs and pharmaceutical intermediates.
As an important chemical raw material and a “universal organic solvent” with strong dissolving power, DMF is mainly used as a washing and curing agent in the synthesis industry such as polyvinyl chloride and polyacrylonitrile, dry spinning of acrylic fibers, and pharmaceutical synthesis intermediates in the pharmaceutical industry. , pesticides in the pesticide industry, dye solvents in the dye industry, quenching of tin-plated parts and cleaning of circuit boards in the electronics industry, etc. Other industries include as a carrier for hazardous gases, as a stationary phase in gas-liquid chromatography, as a solvent for the crystallization of pharmaceuticals, as a binder, and more.
DMF can also form complexes with many substances such as hydrochloric acid, sulfur trioxide, boron trifluoride, etc., which also has very important industrial significance. At present, the main application of DMF in China is the dry spinning of wet synthetic leather and acrylic fiber. Due to the increase in the content of toxic chemical reagents and pesticide standards, the application of DMF in the pesticide industry has gradually decreased. DMF has good thermal and chemical stability, and will not decompose even when heated to the boiling point in the absence of acids, bases and certain halogenated hydrocarbons. At 350°C or higher, DMF undergoes a decomposition reaction to generate carbon monoxide and dimethylamine. When boiling in an aqueous solution, DMF undergoes hydrolysis to generate formic acid and dimethylamine.
- N,N-Dimethylformamide is an exceptional natural solvent, made use of as a solvent for polyurethane, polyacrylonitrile, and polyvinyl chloride, and likewise made use of as an extractant, as a raw material for medications and also chemicals.
- N,N-Dimethylformamide is utilized for plastic movie making; it can also be made use of as a paint stripper for getting rid of paint.
- In the petrochemical sector, n,n-dimethylformamide can be utilized as a gas absorptive to separate and fine-tune gases.
- In natural reactions, n,n-dimethylformamide is not just widely used as a solvent for the response, but likewise an essential intermediate in natural synthesis.
- In the chemical industry, n,n-dimethylformamide can be utilized to generate ciprofloxacin.
- In the pharmaceutical market, n,n-dimethylformamide can be utilized to manufacture iodine, doxycycline, cortisone, vitamin B6, iodine, quercetin, pyrantel, N-formyl sarcomin, antitumor acid, methoxyfenmus, Bian Nitrogen mustard, cyclohexyl nitrosourea, furofluorouracil, hemostatic acid, bepartame, megestrol, bilevita, chlorpheniramine, and so on.
- DMF has a catalytic effect in the reactions of hydrogenation, dehydrogenation, dehydration and also dehydrohalogenation, to make sure that the response temperature is reduced as well as the product pureness is enhanced. Uses Non-aqueous titration solvent. Solvent for plastic and also acetylene. Photometric determination. Gas chromatographic fixed fluid (optimum temperature 50 ℃, solvent is methanol), can separate and also assess C2-C5 hydrocarbons, as well as can divide regular, isobutene as well as cis, trans-2-butene.
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The Preparation Method of N,N-Dimethylformamide
The preparation method of high-purity N,N-dimethylformamide is characterized in that, the extraction step comprises:
- Take the waste liquid N,N-dimethylformamide, add sulfuric acid solution with a volume concentration of 30% to it, and control the pH value within the range of 6 to 8; and mix it with the waste liquid N,N-dimethylformamide Impurities such as organic bases in the amide react to precipitate the reactants from the solution.
- Preheat the N,N-dimethylformamide obtained by the above quenching and tempering to 120°C, the vacuum of the flash tank is 30mmhg, and flash evaporation to remove low-boiling impurities and water.
- The N,N-dimethylformamide obtained by the above distillation is preheated to 70°C, and the air heated to 90°C is introduced to remove residual methylene chloride, methyl tert-butyl ether, water, free amine.
- The N,N-dimethylformamide decompressed rectification after the removal of metal ions is processed, the rectified distillate is tested qualified and then canned, and stored with nitrogen to obtain a medicinal product with a purity of ≥99.9% (wt) Grade N,N-dimethylformamide.
N,N-Dimethylformamide Suppliers and Manufacturers
As a dimethylformamide supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best dimethylformamide raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for dimethylformamide and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.