Methylisothiazolinone CAS 2682-20-4 2-Methyl-4-Isothiazolin-3-one
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Factory Supply Methylisothiazolinone CAS 2682-20-4 2-Methyl-4-Isothiazolin-3-one with Best Price
- Appearance: Yellow liquid
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Methylisothiazolinone Supplier & Manufacturer
Methylisothiazolinone: The Complete Guide
- Item 1: Basic Info
- Item 2: What is Methylisothiazolinone?
- Item 3: Methylisothiazolinone Uses
- Item 4: The Manager has Something to Say
- Item 5: Application of Methylisothiazolinone in Cosmetic
- Item 6: Harm
- Item 7: Quality Control of Methylisothiazolinone
- Item 8: Hot Sale Products
- Item 9: Get Methylisothiazolinone Quotation
Methylisothiazolinone for Sale
Basic Info
Basic Info
| Chemical Name: | Methylisothiazolinone |
| Other Name: | 2-Methyl-4-Isothiazolin-3-one; 5-Chloro- Methyl-4-thiazoline-3-ketone(MI) |
| CAS: | 2682-20-4 |
| EINECS: | 220-239-6 |
| Type: | Raw materials for cosmetics; Raw materials for detergents; Intermediates for pharmaceuticals and synthetic materials; Organic raw materials |
| Molecular Formula: | C4H5NOS |
| Molecular Weight: | 115.15 |
Chemical Properties
Melting point | 254-256 °C(lit.) |
Boiling point | bp0.03 93° |
density | 1.25 (14% aq.) |
vapor pressure | <0.1 mm Hg ( 25 °C) |
storage temp. | 2-8°C |
solubility | Chloroform, Ethyl Acetate |
pka | -2.03±0.20(Predicted) |
form | neat |
color | Yellow |
Water Solubility | 489g/L at 20℃ |
Other Info
| Brand Name: | Zhishang Chemical |
| Provide: | Methylisothiazolinone MSDS; Methylisothiazolinone COA |
What is Methylisothiazolinone?
Methylisothiazolinone (MIT) is a brand-new fungicide imported from Europe in my nation. Isothiazolinone organic compounds can prevent the growth as well as reproduction of numerous microbes (such as germs, fungis, yeast, etc), as well as are a course of broad-spectrum fungicides that are extensively used. Compared with various other sorts of fungicides, isothiazolinone fungicides have the advantages of noticeable effect and also quick activity rate in controlling the development and also metabolism of microorganisms as well as preventing the formation of biofilm.
Isothiazolinone is a water therapy agent with exceptional efficiency and also good miscibility. It can be miscible with various deterioration preventions such as chlorine, range inhibitors as well as dispersants, and also a lot of anionic, cationic as well as nonionic surfactants. It is offered in the marketplace Commercial products in circulation are generally a mix of 5-chloro-2-methyl-4-isothiazolin-3-one (CMI) and also 2-methyl-4-isothiazolin-3-one (MI), while Metal nitrite or metal nitrate will additionally be included in boost stability and prevent decay. The device of activity of isothiazolinone is to eliminate germs by damaging the bonds of microorganisms and also algae proteins. After contact with microorganisms, it can swiftly and irreversibly Hinder its growth, therefore resulting in the death of microbial cells, as well as has a strong inhibitory and also murder effect on common bacteria (sulfate lowering bacteria, sludge developing microorganisms), fungis (iron oxidizing bacteria, mold and mildew, yeast), algae, etc. It has the features of high biocidal effectiveness, great degradability, no residue, risk-free procedure, great compatibility, strong security, and low cost of use. At high doses, it has a significant impact on organic scum removing, as well as has been commonly used in iron and also steel smelting, oil area water shot, thermal power generation, papermaking, oil refining, chemical market, textile, commercial cleaning, pesticides, reducing oil water-based finishes, everyday chemicals, inks, dyes, leather and also various other areas.
Methylisothiazolinone Uses
- 2-Methyl-4-isothiazolin-3-one is a bactericide and preservative based on isothiazolinone, which is used for personal care products. 2-Methyl-4-isothiazolin-3-one is also used to control microbial growth in aqueous solution.
- It is typically utilized as a chemical in bath liquid, shampoo and cleaning agent, as well as can be utilized in cooling water, flowing water, paper making as well as paint finishing in industry.
- Methylisothiazolinone is an antiseptic substance widely made use of in cosmetics. It is a call irritant and also sensitizer. Methylisothiazolinone has just recently been determined as a neurotoxin. Repetitive exposure will harm nerve endings.
- Methylisothiazolinone, occasionally called MIT, is a preservative utilized in cosmetics as well as appeal items. It is a powerful fungicide, or “a chemical that can eliminate living organisms, typically in a careful method”. Bactericide is a general term, consisting of antibacterial agent, bactericide, antibiotic as well as antifungal agent. Finally, methyl isothiazolinone is utilized to avoid different germs and fungi from expanding in cosmetics and charm products, the most typical is shampoo. It is just accepted for wash-type formulations and has a low focus.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
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- Phone: +86 176 5311 3209
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If you want to buy methylisothiazolinone, pls contact us to get a free quote.
Application of Methylisothiazolinone in Cosmetic
The activity of MI is quite high, and the persistence is very good. Due to the high safety of use, it can be promoted in resident products, face creams, sunscreen skin care products and paper towels, small towels, and Z-blade anti-dandruff shampoos all have huge potential markets. Internationally, Rohm and Haas has conducted a comprehensive toxicity and stability test on its Ncolone950. International colleagues and friends in the daily chemical industry can be used as a reference. The challenge test shows that the compound of 9.5% methylisothiazolinone and methylparaben and propyl acetate is in anionic emulsion (9.5% methylisothiazolinone: methylparaben: paraben Propyl vinegar = 0.005:0.2:0.1) and high SPF sunscreen medium both passed the 4-week challenge test. It can maintain good stability in skin care products with high protein nutrients. In shampoos containing zine, the active substance retention rate was still 100% after 4 weeks.
Regarding the use of the compound of methylisothiazolinone and other commonly used bactericidal preservatives (IDBc, DMDMH, parabens, etc.) in the antiseptic of cosmetics, there are the following points of view: first, the compound effect is better than that used alone, The advantages of different preservatives can be used to achieve “complementary advantages”; second, the economic feasibility is better, and because the aqueous solution of methylisothiazolinone does not contain organic salts, no protective agent can be added during compounding, making compound Matching becomes easier.
Harm
Hazard 1: According to a study by the American Society for Cell Biology, the fungicide methylisothiazolinone (MIT) hindered the growth of neurons in fertile rats.
Hazard 2: Elias Aizenman of the University of Pittsburgh School of Medicine believes that methylisothiazolinone can not only cause dermatitis and allergic reactions, but may also affect developing embryos.
Hazard 3: In the report, the British doctor asked to suspend the use of this preservative immediately, because many patients had acute dermatitis, redness and swelling of the face.
Hazard 4: The British Association of Dermatologists warned that the allergy rate caused by this preservative is rapidly increasing, which may cause skin allergies or eczema outbreaks, calling for a ban. The British Skin Allergy Association pointed out that nearly 10% of patients are allergic to this preservative.
Reference
- Methylisothiazolinone – WikiPedia
- Li Chengbei, Zhang Shouyi. Preparation of the latest popular 2_methylisothiazolinone_MI_bactericidal preservative and its application in cosmetics[J]. 2005 (Fifth) China Daily Chemical Industry Symposium
Methylisothiazolinone Suppliers and Manufacturers
As a methylisothiazolinone supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best methylisothiazolinone raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for methylisothiazolinone and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Methylisothiazolinone
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