Hot selling high quality Emtricitabine 143491-57-0

Basic Info

Model No.: LYN- 143491-57-0

Shelf Life: 2 Years

Form:: Powder

CAS: 143491-57-0

Name:: Emtricitabine

Additional Info

Packaging:  25kg/Drum

Productivity: 10000kg

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

HS Code: 143491-57-0

Port: Shanghai,Tianjin,Qingdao

Product Description

Hot selling high quality Emtricitabine 143491-57-0 

Emtricitabine
 
Product name: emtricitabine
Alias:SM-Q;4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-(2r-cis)-2(1h)-pyrimidinone;(-)-BETA-2′,3′-DIDEOXY-5-FLUORO-3′-THIACYTIDINE;EMTRITABINE;FUMITREMORGIN C;EMTRICITABIN;4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
CAS No.: 143491-57-0
Molecular Weight: 247.2467
Molecular Formula: C8H10FN3O3S
InChI:InChI=1/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,( 57307672,H2,10,11,14) 
Density: 1.829g/cm3
Melting point: 136-140°C
Boiling Point: 443.281°C at 760 mmHg
Flash point: 221.889°C
 

 COA of Emtricitabine

 

Item

Requirements

Test Results

Description

A white or almost white crystalline powder

white crystalline powder

Solubility

Freely soluble in Methanol and Water; Practically insoluble in

Dichloromethane

Complies

Identification

The infrared absorption spectrum is

concordant with the spectrum

obtained from Emtricitabine RS or

with the reference spectrum of

Emtricitabine

Complies

 

Determine the Specific Optical Rotation using a 

2.5 mg/ml solution in water R and calculate with reference to the 

dried substance;

 [α]D20 °C = -105.0° to -115.0°.

-107.5°

Limit of Emtricitabine

 Enantiomer

≤0.30%

Not detected

Loss on Drying

≤0.5%   (3 hours at 105°C)

0.14%

Residue on Ignition

≤0.1%

Complies

Related Substance

Any impurity before the principal   Peak   ≤0.5%

Complies

 

Not more than 2 impurities over 0.1%  before the principal peak

Complies

 

Any impurity after the principal peak  ≤0.7%

Complies

 

Not more than 2 impurities over 0.1%  after the principal peak

Complies

 

Total impurities   ≤1.0%

0.10%

Residual Solvents

Ethanol ≤0.30%

0.14%

 

Dichloromethane ≤ 0.06%

Not detected

 

DMF ≤ 0.088%

Not detected

 

Triethylamine ≤ 0.032%

Not detected

 

Toluene NMT 0.089%

Not detected

Heavy Metals

≤20ppm

Complies

Assay

99.0% – 101.0%

100.1%

Conclusion

Meets the Requirements

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