High quality Isatin CAS 91-56-5

High quality Isatin CAS 91-56-5

Isatin is an indole derivative.

Prodution method 

1. First, the acetanilide trichloroacetaldehyde oxime condensation obtained indole acetanilide, and then cyclization, hydrolysis to make ochre.
2. After dissolving sodium carbonate, sodium nitrite, acetic acid, ice and water, stir and introduce sulfur dioxide gas under stirring until the pH is 1, and control the temperature during the process to no more than 10°C. After the reaction was completed, steam was blown to raise the temperature to more than 30°C. The resulting sodium salicyl sulfonate is added with trichloroacetaldehyde, anhydrous sodium carbonate, fully stirred until dissolved, then added with aniline, and steamed, heated to boiling for 2 – 3 min, allowed to stand for 1 – 1.5 h, and cooled to crystallize completely. ,drying. The resulting isonitrosoacetanilide was added in portions to concentrated sulfuric acid at 50° C., while stirring thoroughly, and indirectly cooled with cold water, maintaining the temperature between 60 and 75° C. When the addition of isonitrosoacetanilide was completed, the temperature was raised to After 80 to 10 minutes, the reaction solution was poured into cold water, allowed to stand, crystallized completely, filtered, and washed with water to neutrality to obtain a crude product. The crude product was acid-base precipitated and recrystallized from ethanol to obtain 2,3-dione oxime. The process reaction is:
3 method: In a 2L reaction flask equipped with a stirrer, thermometer, dropping funnel, add indigo …
use
The product is used as an intermediate for dyes and pharmaceuticals, and is used for the production of pharmaceuticals such as cinchon and dye-dispersive yellow E-3G. In chemical analysis, it is a reagent for the determination of cuprous ion, mercaptan, thiophene, and urine blue mother.

Our Services

1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.

3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.

4.Quick and clear response to customers questions.

Warm after sale service, we will help to solve the problems in your usage.

5.We could make our price discount if you place a substantial order with us.

why choose us ? 

1.Full experience of large numbers containers loading in Chinese sea port.

2.Fast shipment by reputed shipping line.

3.Packing with pallet as buyer’s special request.

4.Best service after shipment with e mail.

5.Cargoes together with container sales service available.

6.Full experience for Canada & Japan export.

7.Cargoes photo before and after loading into container.

8.Raw materials from Chinese origin.

FAQ

Q1. Are you a manufacturer

Answer: Yes, we have our own factory called [ZhiShang Industry Group “, we export by ShandongZhishangchemical Co., Ltd. 

Q2. Do you have GMP or DMF

Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation

Answer: -Quality you require, eg. Assay, Purity, or single impurity

-Quantity you need

-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment

Answer: Escrow and T/T in advance are highly recommended. We can accept Western Union, Money Gram and Paypal as well

Q5. When will you deliver the goods

Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment. 

Q6. How will you deliver the goods

Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping.

You also can choose your own shipping forwarder.

Q7. When will we receive the goods

Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most. 

Q8. What if we find your products unsatisfied

Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.

Product expansion

1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the Raw Material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories.

2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.

3> Fragrance And Spices: Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion.

6> Pharmaceutical Intermediates: The so-called pharmaceutical intermediates, refers to the production of pharmaceutical products in the process, the use of raw materials, materials, accessories and other intermediate products.

7> Agricultural Chemicals: Research and agriculture related chemical, including pesticide, plant growth regulator, fertilizer, compound fertilizer, herbicide etc.