Dimethyl Malonate CAS 108-59-8
Previous
Next
Factory Supply Dimethyl Malonate CAS 108-59-8 with Best Price
- Appearance: Colorless liquid
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Dimethyl Malonate Supplier & Manufacturer
Dimethyl Malonate: The Complete Guide
- Item 1: Basic Info of Dimethyl Malonate
- Item 2: What is Dimethyl Malonate?
- Item 3: Dimethyl Malonate Uses
- Item 4: The Manager has Something to Say
- Item 5: Preparation of Dimethyl Malonate
- Item 6: Reference
- Item 7: Quality Control of Dimethyl Malonate
- Item 8: Hot Sale Products
- Item 9: Get Dimethyl Malonate Quotation
Dimethyl Malonate for Sale
Basic Info of Dimethyl Malonate
Basic Info
Chemical Properties
Other Info
Basic Info
Chemical Name: | Dimethyl Malonate |
Other Name: | Dimethylmalonate; Dimethyl propanedioate; Di methyl malonate; Malonic acid dimethyl ester; Dimethyl Malonate cas no 108-59-8 |
CAS: | 108-59-8 |
EINECS: | 203-597-8 |
Type: | Pharmaceutical raw materials; Organic raw materials; Organic intermediates; Pharmaceutical intermediates |
Molecular Formula: | C5H8O4 |
Molecular Weight: | 132.11 |
Chemical Properties
Melting point | -62 °C (lit.) |
Boiling point | 180-181 °C (lit.) |
density | 1.156 g/mL at 25 °C (lit.) |
vapor density | >1 (vs air) |
vapor pressure | 0.15 hPa (20 °C) |
refractive index | n20/D 1.413(lit.) |
Fp | 194 °F |
storage temp. | Store below +30°C. |
solubility | alcohol: miscible |
pka | 11.80±0.46(Predicted) |
form | Liquid |
color | Clear colorless |
explosive limit | 1.3-17.4%(V) |
Water Solubility | negligible |
Stability: | Stable. Incompatible with strong oxidizing agents. Flammable. |
Other Info
Brand Name: | Zhishang Chemical |
Provide: | Dimethyl Malonate MSDS; Dimethyl Malonate COA |
What is Dimethyl Malonate?
Dimethyl malonate is a diester derivative of malonic acid. It is a typical reagent in organic synthesis, for example, as a precursor of barbituric acid. It is additionally utilized in the synthesis of malonate. It can be manufactured from Dimethoxymethane and carbon monoxide.
Dimethyl malonate, likewise called Dimethylmalonate, is a general-purpose natural reagent. As an important organic synthesis raw material, dimethyl malonate can take part in various sorts of chain reactions, including: hydrolysis, decarboxylation, alkylation, Michael response, Knoevenagel response, nitrosation reaction as well as other reaction kinds, which additionally identify its broad use in the field of natural synthesis.
In a nutshell, dimethyl malonate is a crucial pharmaceutical intermediate as well as a crucial resources for the synthesis of fragrances, dyes, anti-oxidants, light stabilizers as well as several other fine chemicals. As well as the world need is very large, with an annual demand of 10,000 bunches. At present, dimethyl malonate abroad is mainly used as a resources for the production of pipemidic acid by non-ethoxymethylidene procedure, as well as reacts with orthoformate as well as urea to produce pipemidic acid. With the exception of export, the majority of the dimethyl malonate produced by associated enterprises in my country is made use of to create pipemidic acid.
Dimethyl Malonate Uses
- Dimethyl malonate is a reagent used in natural synthesis. It is a precursor for the synthesis of monosubstituted and also disubstituted acetic acids, barbiturates, vitamin B1 as well as vitamin B6.
- Dimethyl malonate is used in perfumes as well as some synthetic perfumes.
- Dimethyl malonate is a vital basic material for the manufacturing of pharmaceutical pipemidic acid. Dimethyl malonate abroad is mainly utilized as a raw material for the manufacturing of pipemidic acid by non-ethoxymethylidene procedure, and reacts with orthoformate and urea to produce pipemidic acid. Today, the majority of the dimethyl malonate generated by related business in my nation is made use of to produce pipemidic acid besides export.
- It is used in the pharmaceutical sector to prepare chloroquine, buconazoline and also other medications. Dimethyl malonate reacted with 1,3-diphenylprop-2-enyl acetate in an enantioselective palladium militarized allyl substitution response to generate diastereomeric pure thiophenylpyridine.
- Dimethyl malonate is made use of for gold militarized oxidative esterification of glycerol, 1,2-propanediol and also 1,3-propanediol.
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
Contact Us
- Email: sales002@sdzschem.com
- Phone: +86 176 5311 3209
- WhatsApp: +86 176 5311 3209
- WeChat: Zhishang17653113209
- Skype: +86 176 5311 3209
Facebook
Twitter
LinkedIn
Pinterest
Email
WhatsApp
If you want to buy dimethyl malonate, pls contact us to get a free quote.
Preparation of Dimethyl Malonate
The prep work of cyanoacetic acid: make use of 20) 3 to manage chloroacetic acid remedy, make its pH worth between 7.0-7.5; Sodium cyanide solution is added salt chloroacetate solution, executes cyanidation in between specific 100-110 ℃ Response; Add focused hydrochloric acid to execute acidification response in the cyanide remedy, after the reaction is accomplished for a time period, vacuum cleaner concentration, dehydration till the weight proportion of cyanoacetic acid as well as water is in between 2-3: 1;
Esterification: in the remedy of cyanoacetic acid, include the hostility oil, include 4-6 times the methanol as well as catalyzer of chloroacetic acid weight, catalyzer contains 8-10% weight percent lead chloride, 65-72% weight percent triphenylphosphine, 10-15% weight percent dimethyl sulfoxide and 8-12% weight percent hydrazine hydrate, at 60 ℃ -80 ℃ temperature level, continue to react 5-6 hrs, vapor excess methanol at regular pressure, and also the unrefined product is After neutralization, water cleaning and drying, the product is dimethyl malonate acquired by correction.
Reference
- Dimethyl malonate – WikiPedia
- Dimethyl malonate – PubChem
Dimethyl Malonate Supplier and Manufacturer
As a dimethyl malonate supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best dimethyl malonate raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for dimethyl malonate and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Service
FAQ
Shipping
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of Dimethyl Malonate
Previous
Next
