Colchicine used as Antitumor drugs 64-86-8

Basic Info

Model No.: X-CAS 64-86-8

CAS:: 64-86-8

MF:: C22H25NO6

MW:: 399.43700

Appearance:: Yellow Powder

MP:: 150-160 °C (dec.)(lit.)

FP:: 392.9ºC

Additional Info

Packaging: 25KGS/Drum

Productivity: 100000kg per month

Brand: ZHISHANG

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE API

HS Code: 64-86-8

Port: Shanghai,Tianjin,Qingdao

Product Description

Colchicine used as Antitumor drugs 64-86-8

Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8 is also known as colchicine, which is a kind of alkaloid extracted from the bulbs of Liliaceae, and the seeds are naturally present in the Liliaceae and Calamagrostis angustifolia, 0.11% and 0.1% The Pale yellow needle crystal. Slightly stinky and bitter. Melting point of 157 ° C, soluble in cold water, alcohol, chloroform and formaldehyde, poor solubility in hot water, insoluble in benzene and ether, almost insoluble in petroleum ether, 0.5% solution pH of 5.9, Toxicity is reduced. Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8 inhibits cell mitosis and anti-tumor effects. In 1889 the Italian scholar Perniche first discovered the effect of colchicine on mitosis, he described the division of the gastrointestinal wall of the dog’s stomach was inhibited by colchicine, the spindle was destroyed, the chromosomal action was paralyzed, and normal Mitotic cells remain in the middle. 

This is caused by colchicine is not normal split called colchicine mitosis (referred to as C mitosis). In colony analysis and polyploid mutagenesis, Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8 is one of the most widely used chemical agents. The concentration of its aqueous solution and its role in a positive correlation, the higher the concentration, the stronger the role. Various plants and different tissues have different responses to colchicine. To sum up, the young and splitting tissue (such as germination of the seeds of germ) treatment time can be shorter, the concentration should be lower; the other side of the treatment time can be longer, the concentration should be higher.

The effective concentration of Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8 treatment is 0.01 ~ 0.4%, and the application range is about 0.2%. Such as the concentration of 0.2 ~ 0.4% of the Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8 solution drops in the diploid watermelon seedling growth point, once a day for 4 days, and  shade to maintain humidity, Active Pharmaceutical Ingredients(API) can induce tetraploid watermelon. For cereal crops, such as rice, you can have more than four true leaves of the robust seedlings in the root neck cut a mouth, not to cut the growth point for the degree, immersed in 0.025 ~ 0.05% of colchicines solution, submerged incision , From 8 to 14 days (20 ℃) can also be tetraploid plants. At present, Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8 is widely used in anthers (powders), and the chromosomes of the resulting haploid plants are doubled in ovary.


 Description:

Product Name

Colchicine Active Pharmaceutical Ingredients(API) cas 64-86-8
Latin Name

Colchicum autumnale L.

Plant source

The bulb of the Colchicum autumnale L.

Heavy metal

≤8PPM

Pesticides

Negative

Loss on drying

≤5%

Specification

Colchicine 98%  99%

CAS No

64-86-8 ( Colchicine )


Packing ahd shipping 
25KGS/Drum or as your request.
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

Our Advantage
1.Stable quality, high quality satisfy customer’s high grade sourcing request.
2.Competitive price .
3.Correct delivery time promise.
4.Continuous improvement make sure the long-term cooperation.
5.Honest service for your whole sourcing process

Services
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
4.Quick and clear response to customers questions.
5.Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.


Product expansion

1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the Raw Material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories.

2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.

3> Fragrance And Spices: Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion.

6> Pharmaceutical Intermediates: The so-called pharmaceutical intermediates, refers to the production of pharmaceutical products in the process, the use of raw materials, materials, accessories and other intermediate products.

7> Agricultural Chemicals: Research and agriculture related chemical, including pesticide, plant growth regulator, fertilizer, compound fertilizer, herbicide etc.

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