China manufacture support Antipyrine cas no. 60-80-0

Basic Info

Model No.: LYN- Antipyrine

CAS: 60-80-0

Name:: Antipyrine

Shelf Life: 2 Years

Sample: Available

Additional Info

Packaging:  25kg/Drum

Productivity: 10000kg

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

HS Code: 1060.24000

Port: Shanghai,Tianjin,Qingdao

Product Description

China manufacture support Antipyrine cas no. 60-80-0 

Product Introduction

Product Name Antipyrine/Phenazone
Synonyms 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone
CAS No. 60-80-0
EINECS 200-486-6
Molecular Formula C11H12N2O
Molecular Weight 188.23
Appearance Colorless powder
Melting point 109-113 ºC
Assay 99%

 Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.Phenazone, also known as phenazon, antipyrine, or analgesine, is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic. It was first synthesized by Ludwig Knorr in 1883. It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid. Phenazone has an elimination half life of about 12 hours.

Function/Usage: 

   Used to relieve pain and fever. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.

Specification

Item

Standard

Results

Characteristics

Colorless or white crystal

conforms

Melting Point

110-113°C

110.1-111.2°C

Identification

Positive

Positive

Chloride

Not more than 100ppm

conforms

Sulphate

Not more than 100ppm

Conforms

Sulphated Ash

Not  more than 0.1%

Conforms

Heavy Metals

Not More than 20ppm

<20ppm

Colour of solution

Conforms

Conforms

Acidic or Alkalinic Substances

Conforms

Conforms

Loss on Drying

Not more than 1.0%

0.2%

Assay(On dry basis)

99.0-100.5%

99.7%

Conclusion

Complies with BP2004

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