CAS NO 143-15-7 1-Bromobutane

production method:
1. From lauryl alcohol (n-dodecanol) and hydrobromide derived role: The lauryl alcohol was added to the enamel glass reaction kettle, stirring and cooling, slowly adding sulfuric acid. Stir 1h, then add hydrobromic acid. Gradually increase the temperature to 90 ~ 95 ° C, the reaction was stirred 8h. The reaction is completed, cooled to 30 ° C for 8h. Separation of acid layer, the reservoir dilute lye adjusted pH8, points to lye, washed with 50% ethanol. Vacuum distillation, collecting 140 ~ 200 ℃ (3.33kPa) distillate products. Yield more than 90%.
2. Method: In equipped with a stirrer, thermometer, ventilation catheter reaction flask was added n-dodecanol
(2) 186g (1.0mol), heated to 100 ° C with stirring, a dry hydrogen bromide gas is passed through the reaction, maintaining the reaction temperature between 100 ~ 120 ℃, until the solution is no longer absorbed hydrogen bromide. Add water after cold 70mL, shake fully, the separation of the water layer. The organic layer was added with 1/3 volume of concentrated sulfuric acid, and the mixture was thoroughly shaken to separate the acid layer, washed successively with water, 10% sodium carbonate and 50% methanol, dried over anhydrous calcium chloride and distilled under reduced pressure to collect 130-135 /0.8kPa distillate to give 1-bromo dodecane …
use:
Mainly used in organic synthesis, used in medicine for the synthesis of disinfectants benzalkonium bromide, and so on.

Product expansion
1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the raw material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories. The former is a class of cosmetics in the main raw materials, cosmetics in the possession of a large proportion of the cosmetics play a major role in the role of the material. The latter is the formation of cosmetics, stability or to give color, smell and other characteristics of the role of these substances in the cosmetic formula is not used, but it is extremely important. Cosmetics are natural, synthetic or extracted from the role of different substances as raw materials, by heating, mixing and emulsification and other production processes processed from the chemical mixture.
2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.It is one substance or mixture during the medicine making period, it can not be taken directly by patients.
3> Fragrance And Spices: Spice is a substance that can be scented by smelling or scented by taste, and is the raw material for the preparation of the fragrance. Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.
4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, pesticides, pharmaceuticals, resins, additives, and other intermediates.
5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion, usually in resin, or oil, or emulsion is given priority to, add or not add pigment, filler, add the corresponding additives, organic solvents or water preparation of viscous liquid.