CAS 6119-47-7 Quinine hydrochloride dihydrate

Basic Info

Model No.: X-CAS 6119-47-7

CAS No.:: 6119-47-7

Name:: Quinine Hydrochloride Dihydrate

MF:: C20H29ClN2O4

MW:: 396.90800

MP:: 115-116 °C (dec.)(lit.)

Bp:: 633ºC At 760 MmHg

FP:: 122 °C

Additional Info

Packaging: according to your request

Productivity: 100000kg per month

Brand: ZHISHANG

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

HS Code: 29392000

Port: Shanghai,Tianjin,Qingdao

Product Description

Quinine Hydrochloride is an alkaloid of cinchona that was once widely used to control and prevent malaria; it also has analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and it decreases the excitability of the motor end plate. It is used as the dihydrochloride, hydrochloride, or sulfate salt in the treatment of resistant falciparum malaria.

 

Quinine Hydrochloride occurs naturally in the bark of the cinchona tree, though it has also been synthesized in the laboratory. The medicinal properties of the cinchona tree were originally discovered by the Quechua, who are indigenous to Peru and Bolivia; later, the Jesuits were the first to bring cinchona to Europe.

 

Quinine Hydrochloride can cause abnormal heart rhythms, and should be avoided if possible in patients with atrial fibrillation, conduction defects or heart block. Quinine can cause hemolysis in G6PD deficiency (an inherited deficiency), but this risk is small and the physician should not hesitate to use quinine in patients with G6PD deficiency when there is no alternative

Function:

1).Antimalarial,Antiarrhythmic     

2).As an antipyretic (antifever) agent especially useful in treating malaria.

Specification:

ITEMS ITEMS TEST RESULT
DESCRIPTION A white or almost white powder Complies
SOLUBILITY Very soluble in water; soluble in ethanol (99%) Complies
MELTING POINT 233-235 ºC 234ºC
SPECIFIC OPTICAL ROTATION -223-229° (C=2, 0.1M HCl) -241º
SULPHATED ASH ≤0.1% 0.05%
BARIUM This product is 0.2g, dissolved in 10ml water, add dilute sulfuric acid 1ml, 15 minutes, turbidity shall not occur Complies
THE RELATED IMPURITIES ≤ 1.5% 0.90%
LOSS ON DRYING 6.0%-10.0% 8.00%
RESIDUE ON IGNITION ≤ 0.15% 0.05%
 PH 2.0-3.0 2.5
ASSAY 99.0%-101.0%                           99.20%

Product expansion

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2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.

3> Fragrance And Spices: Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion.

6> Pharmaceutical Intermediates: The so-called pharmaceutical intermediates, refers to the production of pharmaceutical products in the process, the use of raw materials, materials, accessories and other intermediate products.

7> Agricultural Chemicals: Research and agriculture related chemical, including pesticide, plant growth regulator, fertilizer, compound fertilizer, herbicide etc.

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