CAS 298-12-4 Glyoxylic acid with free sample

Basic Info

Model No.: X-CAS 298-12-4

Type: Pharmaceutical Intermediates

Appearance: Liquid

Colour: Yellow

Appearance:: Colorless Or Light Yellow Liquid

Usage:: Pharm Intermediates

Packing:: 250kg/plastic Drum

Boiling Point:: 111°C

Density:: 130-136 °C

MF:: C2H2O3

Assay:: 99.0%min

Molecular Weight:: 202.63

Application:: Pharm Intermediates

EINECS No.:: 206-058-5

Additional Info

Packaging:  200 kg/drum

Productivity: 1000kg per Month

Brand: zhishang

Transportation: Ocean,Land,Air

Place of Origin: Shandong, China (Mainland)

Supply Ability: in stock

Certificate: ISO CE

HS Code: 2918300090

Port: Shanghai,Qingdao,Tianjin

Product Description

Introduction oPharmaceutical Intermediates

1. Glyoxylic acid Pharmaceutical Intermediates consists of an aldehyde group (-cho) and a carboxyl group (-cooh), whose structure is HOCCOOH, molecular C2H2O3. Production methods:1. The solution of oxalic acid electrolytic acid solution has been reduced by electrolysis, producing acetaldehyde dilute solution, and then by evaporation, concentration, freezing and filtration gradually enriched, finally the packaging of the quality products.

2. Glyoxal oxidation Pharmaceutical Intermediates of acetaldehyde is oxidized by air or oxygen under the action of the catalyst, resulting in glyoxalic acid, which is then refined and purified. In addition, dichloroacetic acid is condensed with methanol sodium and sodium dimethoxyacetic acid is obtained.

3. The method of dichloroacetic acid sodium methanol and methanol in reaction tank and heated to 40 ~ 50 ℃, slowly add dichloroacetic acid, reflux reaction 2 h after complete, condensation, then cool to room temperature, filtering, methanol washing, wash filtrate the merger, a quick dimethoxy sodium acetate methanol solution. Solutions of the reduced pressure concentration to dry, add 2.8 servings of hydrochloric acid on the water bath heating, and stir into a paste and hydrolysate, up to 90 ℃, cold from around 10 ℃, filtration, separation, a quick finished product…


Pharmaceutical Intermediates is used as a perfumer and flavouring agent for cosmetics and also for pharmaceutical products.

production method of Pharmaceutical Intermediates

1. Oxalic acid electrolysis oxalic acid aqueous solution by electrolysis reduction, resulting in dilute glyoxylic acid solution, and then by evaporation, concentration, freezing, filtration gradually concentrated, and finally qualified packaging.

2. Glyoxal oxidation Pharmaceutical Intermediates in the role of the catalyst by air or oxygen oxidation, the formation of glyoxylic acid, and then refined by the finished product. In addition, dichloroacetic acid and sodium methoxide condensation of sodium dimethoxy acetic acid, and hydrochloric acid hydrolysis to generate glyoxylic acid.

3. Dichloroacetic acid method of sodium methoxide and methanol into the reaction tank, heated to 40 ~ 50 ℃, slowly dropping dichloroacetic acid, after the completion of reflux reaction 2h, condensation is completed, and then cooled to room temperature, filtration, methanol washing , Combined to wash the filtrate, that was dimethoxy acetic acid sodium methanol solution. The solution was concentrated under reduced pressure to dryness, and 2.8 parts of hydrochloric acid was added to the water bath and heated to a paste to obtain a hydrolyzate. The temperature was raised to 90 ° C and cooled to about 10 ° C. The mixture was filtered and separated to obtain a product

Usage of Pharmaceutical Intermediates

Glyoxylic acid Pharmaceutical Intermediates  used as a cosmetic flavoring agent and fixing agent, also used in pharmaceuticals.

Our Advantage

1.Stable quality, high quality satisfy customer’s high grade sourcing request.

2.Competitive price .

3.Correct delivery time promise.

4.Continuous improvement make sure the long-term cooperation.

5.Honest service for your whole sourcing process


1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.

3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
4.Quick and clear response to customers questions.
5.Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.

Product expansion

1> Cosmetic Raw Materials: Cosmetics is a variety of raw materials through a reasonable deployment of processing from the compound mixture. Cosmetics with a wide range of raw materials, different performance. According to the Raw Material properties and uses of cosmetics, can be divided into matrix materials and auxiliary raw materials in two categories.

2> Active Pharmaceutical Ingredients(API): API refers to the raw materials in the production of various types of preparations, which is the active ingredient in powder,crystal and paste for medicine use through chemical synthesis,plant extract, and preparations of biotechnology institute.

3> Fragrance And Spices: Spices are an important part of fine chemicals, it is composed of natural spices, synthetic spices and single fragrance.

4> Organic Raw Material: Intermediates are also known as organic intermediates. The use of coal tar or petroleum products as raw materials to produce dyes, resins, additives, and other intermediates.

5> Chemicals Used In Paints: Paint, the traditional Chinese name is paint. So-called coating is coated on the surface of the object that be protected or be adornment, and with the continuous film coating to form strong adhesion.

6> Pharmaceutical Intermediates: The so-called pharmaceutical intermediates, refers to the production of pharmaceutical products in the process, the use of raw materials, materials, accessories and other intermediate products.

7> Agricultural Chemicals: Research and agriculture related chemical, including pesticide, plant growth regulator, fertilizer, compound fertilizer, herbicide etc.

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