Amino-2-Propanol CAS 78-96-6
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- Appearance: Colorless liquid
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: Amino-2-Propanol Supplement
Amino-2-Propanol: The Complete Guide
Amino-2-Propanol for Sale
Basic Info of Amino-2-Propanol
2 Amino 2 methyl propanol; 1-Amino-2-propanol; DL-IsopropanolaMine; (±)-1-Amino-2-propano; 1-Aminopropan-2-ol
Pharmaceutical raw materials; Organic raw materials
What is Amino-2-Propanol?
1-Aminopropan-2-ol is an organic compound with the chemical formula CH 3 CH (OH) ch2nh 2. It is an amino alcohol. The term isopropanolamine can also refer more generally to other homologues diisopropanolamine (Dipa) and triisopropanolamine (TIPA).
1-Aminopropan-2-ol is chiral. It can be prepared by adding ammonia water to propylene oxide.
1-Amino-2-propanol (MIPA, Amino-2-Propanol) is an essential great chemical resources with a large range of uses. It is commonly utilized as surfactants, metal functioning fluids, paints and finishes, fabric printing as well as dyeing, individual treatment items, water treatment representatives, and also intermediates of pharmaceuticals and pesticides. One of the raw materials of the body. The main uses of 1-amino-2-propanol (isopropanolamine) are as complies with:
- The response with fat produces fatty acid isopropanolamide (alkyl isopropanolamide) and also ester, due to its excellent lathering buildings, foam stability as well as the capability to dissolve grease, it can be made use of as industrial artificial detergent.
- The item gotten from thioglycolic acid can be made use of as a cosmetic base.
- Because of its good hygroscopicity and also weak alkalinity, it can be utilized as a raw material for surfactants, and can be made use of as improving agents, antistatic representatives, dyeing accessories as well as fiber wetting agents in the fiber industry.
- Its phosphate and also nitrite can be made use of as anti-oxidants for numerous lubricating oils as well as cutting oils.
- The reaction items with numerous acids and greater aliphatic ketones can be used as plasticizers, emulsifiers and solvents. The isopropanolamine mix has a specifically strong dissolving capacity to hydrocarbons. Mix kerosene, halogenated hydrocarbons, naphtha, and so on together with isopropanolamine (4%) as well as oleic acid (15%) in water to get a secure solution. The salts formed with long-chain fats can be made use of as emulsifiers for vinyl acetate resins, with good solution stability and secure shade.
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Application of Amino-2-Propanol
CN201310281153.3 discloses a new process for synthesizing tenofovir disoproxil, using (R)-(-)-1-amino-2-propanol as raw material to react with p-toluenesulfonyloxymethyl diethyl phosphate, Then through hydrolysis and condensation to obtain (R)-2-O-[bis(isopropoxycarbonyloxymethyl)phosphono-methyl]-1-amino-2-propanol (IV), the obtained formula (IV) ) compound is condensed with 5-amino-4,6-dichloropyrimidine, and tenofovir disoproxil is obtained by ring closure and aminolysis. The invention provides a new tenofovir disoproxil synthesis process, which has low production cost, process safety, good product quality and is suitable for industrialized production.
Preparation of Amino-2-Propanol
Propylene oxide and ammonia water with a concentration of 95wt% in a molar ratio of 1:1.0 were respectively input into the mixer with a metering pump, and the temperature in the mixer was controlled to be 0°C and the pressure was 3.0MPa; the mixture was continuously fed into the microchannel for reaction In the reactor, the material reacts in the channel of the reaction section of the reactor, the temperature is 60 °C, the pressure is 3.0 MPa, and after staying for 0.1 s, it enters the cooling section of the microchannel reactor to rapidly cool down to terminate the reaction, the outlet temperature is 0 °C, and the temperature is 0 °C. The time is 2S, and the specific cooling rate is controlled at about 1800-2000°C/min.
Then, the low boilers are removed through a stripping tower to obtain the product 1-amino-2-propanol with a content of 99.2%. In this embodiment, the microchannel reactor is specifically made of stainless steel, wherein the inner diameter of the microchannel is 0.05mm, and the length of the microchannel is 0.8m.