4-Acetoxyindole CAS 5585-96-6
Factory Supply 4-Acetoxyindole CAS 5585-96-6 with Best Price
- Appearance: White powder
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: 4-Acetoxyindole Supplier & Manufacturer
4-Acetoxyindole: The Complete Guide
4-Acetoxyindole for Sale
Basic Info of 4-Acetoxyindole
Ammonium alginate; 1-phenyl-2,3-dimethyl-4-methylamino-5-pyrazolone-N-methanesulfonate sodium; Rovaline; Novaline; ammonium calcium alginate
Food additives; Pharmaceutical raw materials; organic raw materials
What is 4-Acetoxyindole?
4-Acetoxyindole is an indole with acetyl team. It is made use of as the starting reactant for preparing 4-oxoquinoline and also as an anti HIV representative. In chromatographic analysis, it is used to help maximize the peak capability for separating low molecular weight molecules throughout slope elution.
4-Acetoxyindole is a natural intermediate gotten by acylation of 4-hydroxyindole with acetic anhydride.
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Preparation of 4-Acetoxyindole
4-hydroxyindole (1 equiv of restricting reagent) was loaded into the vessel under N2, complied with by DCM (dichloromethane; 4-hydroxyindole based loading, 6 quantities). The response was cooled down to 0-5 ° C, and also pyridine (1.2 equiv.) was added dropwise at 0-5 ° C. Acetic anhydride (1.1 equiv) was included dropwise at 0-5 ° C and also the response was warmed up to 20-25 ° C for 1-1.5 hrs as well as stirred at 20-25 ° C for an extra 3 hrs. The response was tested and analyzed for conclusion. The response was after that washed 3 times with 20% aqueous citric acid solution (4-hydroxyindole based loading, 3 x 3 vol) and when with saturated NaHCO3 (4-hydroxyindole based loading, 3 vol). The DCM option was dried over MgSO4 and filtered, as well as the DCM layer was focused to half volume by purification. Heptane (based on 4-hydroxyindole loading, 6 quantities) was included and also additional DCM was eliminated by distillation till total rainfall of stage 1 occurred. The response was cooled to 15 ° C-25 ° C, as well as the strong was accumulated by filtering, cleaned with heptane (4-hydroxyindole based loading, 1 vol), and dried out under vacuum cleaner at 60 ° C overnight to offer 4-acetoxyindole indoles.
- 4-Acetoxyindole – PubChem
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4-Acetoxyindole Supplier and Manufacturer
As a 4-acetoxyindole supplier and manufacturer with strict standard product quality system certificate, Zhishang Chemical has long been providing the best 4-acetoxyindole raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have demand for 4-acetoxyindole and related products, please contact our service staff Zhishang Chemical – White directly, we will provide you with high-quality products at the best price.
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