3-Dimethylaminopropylamine CAS 109-55-7
Factory Supply 3-Dimethylaminopropylamine CAS 109-55-7 with Best Price
- Appearance: Colorless liquid
- Assay: 99. 0%min
- Stock: In stock
- Sample: Available
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3-Dimethylaminopropylamine: The Complete Guide
3-Dimethylaminopropylamine for Sale
Basic Info of 3-Dimethylaminopropylamine
Dimethyl amino propyl amine; DMAPA; N,N-dimethyl-1,3-propanediamine
What is 3-Dimethylaminopropylamine?
3-Dimethylaminopropylamine (DMAPA) is a diamine used in the preparation of certain surfactants, such as coconut amidopropyl betaine, which is an ingredient of many personal care products, including soap, shampoo and cosmetics. BASF, the main manufacturer, claims that DMAPA derivatives do not hurt eyes and will produce fine foam, making them suitable for shampoo.
Diamines are an important class of chemical substances that are widely used as raw materials, intermediates or products. For example, diamines are necessary structural devices in the process of synthesizing polyamides and also in other polycondensation responses. N,N-Dimethyl-1,3-diaminopropane (DMAPA) is an important intermediate for industrial preparation such as lubricants, in addition, DMAPA is used as a raw material for the preparation of coagulants, which itself should have Corrosion resistance.
- 3-Dimethylaminopropylamine is widely used in the manufacture of cosmetic raw materials, such as palmamide dimethylpropylamine, cocamidopropyl betaine, mink oil amidopropylamine, etc.
- N,N-dimethyl-1,3-propanediamine is an intermediate of the fungicide propamocarb.
- 3-Dimethylaminopropylamine is used as an intermediate in organic synthesis to prepare dyes, ion exchange resins, epoxy resin curing agents, oils and additives for cyanide-free electro-galvanizing, fiber and leather treatment agents and fungicides.
- 3-Dimethylaminopropylamine contains both primary and tertiary amine groups in the molecule. It is used as epoxy resin curing agent with both functions of curing agent and accelerator. Mainly used for laminates, castings and adhesives, etc., the general dosage is 2-6 parts.
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Application of 3-Dimethylaminopropylamine
CN201511019713.3 discloses an artemisinin derivative and a synthesis method and application thereof. The artemisinin derivative is N-(3-N’,N’-dimethylamino-propyl)-10-azadeoxyartemisinin, which uses artemisinin as a raw material and is successively mixed with N. , N-dimethyl-1,3-diaminopropane and p-toluenesulfonic acid reaction.
By investigating the proliferation inhibitory activity of the derivative on various human tumor cell lines and human normal cell lines, the applicant found that it can inhibit human bladder cancer cells T-24, human ovarian cancer cells SK-OV-3, and human gastric cancer cells MGC80- 3 All three cell lines showed significant proliferation inhibitory activity and had good potential medicinal value, and were expected to be used in the preparation of various anti-tumor drugs.
Preparation of 3-Dimethylaminopropylamine
Step 1. Obtain a mixture of acrylonitrile and dimethylamine in a molar ratio of 1:1 to 3, and vaporize the mixture at a temperature of 100 to 120°C to obtain a primary vaporized mixture;
Step 2. The amination reaction is carried out with the primary vaporization mixture under the action of a portion of the activated carrier. The reaction temperature is 100-120° C., the reaction pressure is 0.3-0.5MPa, and the volumetric space velocity of acrylonitrile is 0.1-0.25h-1. Obtain a catalytic mixture;
Step 3. The primary catalytic mixture is vaporized at a high temperature under the condition of 150-180 °C to obtain a secondary vaporized mixture;
Step 4. The secondary vaporization mixture is subjected to hydrogenation reaction under the action of another activated carrier, the reaction temperature is 150-180°C, the reaction pressure is 0.3-0.5MPa; the volume space velocity is 0.1-0.25h-1, and the secondary catalyst;
Step 5, the secondary catalyst is cooled to 40° C., and the liquid phase is collected, and the liquid phase is specifically N,N-dimethyl-1,3-diaminopropane.
- 3-Dimethylaminopropylamine – PubChem
- “BASF ups capacity at DMAPA plant”. Cosmetics Design. 2003-10-28.
- [Chinese invention] CN201911135489.2 Supported catalyst for N,N-dimethyl-1,3-propanediamine and its preparation and application
3-Dimethylaminopropylamine Suppliers and Manufacturers
As a 3-dimethylaminopropylamine supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best 3-dimethylaminopropylamine raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for 3-dimethylaminopropylamine and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.