α-Naphthoflavone CAS 604-59-1
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Factory Supply α-Naphthoflavone CAS 604-59-1 with Best Price
- Appearance: Yellow powder
- Purity: 99. 0%min
- Stock: In stock
- Sample: Available
- Zhishang Chemical: α-Naphthoflavone Supplier & Manufacturer
α-Naphthoflavone: The Complete Guide
α-Naphthoflavone for Sale
Basic Info
Basic Info
| Chemical Name: | α-Naphthoflavone |
| Other Name: | 2-Phenyl-4H-benzo[h]chromen-4-one; alpha-Naphthoflavone |
| CAS: | 604-59-1 |
| EINECS: | 210-071-1 |
| Type: | Plant extracts |
| Molecular Formula: | C19H12O2 |
| Molecular Weight: | 272.3 |
Chemical Properties
Melting point | 153-157 °C (lit.) |
Boiling point | 375.35°C (rough estimate) |
density | 1.1382 (rough estimate) |
refractive index | 1.5510 (estimate) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Crystalline Powder or Crystals |
color | yellow |
BRN | 210862 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
Other Info
| Brand Name: | Zhishang Chemical |
| Provide: | α-Naphthoflavone MSDS; α-Naphthoflavone COA |
What is α-Naphthoflavone?
α- Naphthalene flavone, additionally referred to as 7,8-benzoflavone and 2-phenyl-benzo (h) chrome-4-one, is an artificial flavone derivative, which is an efficient and affordable aromatase prevention with IC50 and Ki worths of 0.5 as well as 0.2 specifically μ M 。
α- Naphthoquinone is a reliable prevention of aromatase, which transforms testosterone right into estrogen. α – Naphthoflavone has been shown to cause irregular testicular development in young chickens.
α-Naphthoflavone Uses
α- Naphthylflavone is used as an indicator of oxidation and reduction.
α- Naphthylflavone is a kind of flavonoids that can act on μ- Opioid receptors to treat pain. It is also used as a non steroidal aromatase inhibitor for the treatment of breast cancer.
The extended flavonoids are produced by the formal fusion of benzene ring and the h side of flavonoids. A synthetic compound that is an inhibitor of aromatase (EC 1.14.14.14).
The Manager has Something to Say
This is William, CEO of Zhishang Chemical Co., Ltd.
Welcome to visit our factory . As the top chemical manufacturer, we have been striving for product quality, innovation , R&D, and customer service for the past 7 years. In the next 10 years or even longer, we are committed to becoming the most reliable chemical supplier in the world , creating a well-known international brand trusted by customers, with the spirit of “one meter wide, ten thousand meters deep”, we continue to focus on product research and development, continue to focus on customer service, continue to improve the supply chain service system, to create a professional chemical supply service team, to achieve win-win long-term cooperation. Please feel free to contact us if you have any questions.
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If you want to buy α-naphthoflavone, pls contact us to get a free quote.
Application of α-Naphthoflavone
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription variable that can advertise the expression of stage I and also phase II allogenic chemical metabolic enzyme genes, including cytochrome P450 (CYP) subtypes CYP1A1 and also CYP1A2. α- Naphthalene flavone is a sort of flavone, which can regulate the metabolism of xenobiotics at numerous points. It annoys AhR and also obstructs the expression of phase I as well as stage II genes at nanomolar focus, although it can obstruct the expression of stage I as well as stage II genes at higher focus (10 μ M) Next fired up AhR. α- Naphthoflavone prevents CYP19 (aromatase), CYP1A1, CYP1A2 as well as CYP1B1 (IC50 is 500, 60, 6 and also 5 nM specifically), while it triggers CYP3A4 (Kd=7.4 μ M ） 。 In the existence of artificial estrogen α- Naphthene flavonoids might cause cancer causing impacts.
Reference
- alpha-Naphthoflavone – WikiPedia
- Kellis JT Jr; Vickery LE (1984). “Inhibition of human estrogen synthetase (aromatase) by flavones”. Science.
α-Naphthoflavone Supplier and Manufacturer
As a α-naphthoflavone supplier and manufacturer with a strict standard product quality system certificate, Zhishang Chemical has long been providing the best α-naphthoflavone raw materials to customers all over the world.
Over the years, relying on professional team experience and customer-centric team concept to meet customer needs in a timely manner, our company enjoys a high reputation in the world. At present, our company has served more than 6,000 customers and has established long-term cooperative relations with customers from many countries.
If you have a demand for α-naphthoflavone and related products, please contact our service staff Zhishang Chemical – White directly, and we will provide you with high-quality products at the best price.
Service
Pre-Sales Service
* Prompt reply and 24 hours online, professional team to provide the best price and high-quality product.
* Sample testing support.
* Every batch of products will be tested to ensure its quality.
* The packing also can be according to the customers` requirement.
* Any inquiries will be replied to within 24 hours.
* We provide a Commerical Invoices, Packing Lists, Bills of loading, COA, Health certificates, and Origin certificates. If your markets have any special requirements, let us know.
After-Sales Service
* The fact of logistics information monitoring.
* Any questions about the product can be consulted at any time.
* Product has any problem can return.
FAQ
Do you accept sample order?
We will make samples before mass production, and after the sample is approved, we’ll begin mass production. Doing 100% inspection during production, then doing random inspection before packing.
What’s your MOQ?
Our MOQ is 1kg. But usually we accept less quantities, such as 100g on the condition that the sample charge is 100% paid.
Is there a discount?
The different quantity has different discount.
HOW TO CONFIRM THE PRODUCT QUALITY BEFORE PLACING ORDERS?
You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Do you supply product report?
Yes. We’ll give you product analysis report before shipping.
Shipping
1. ≤50kg, Express delivery recommended, usually called DDU service;
2. ≤500kg, Air shipping recommended, usually called FOB, CFR, or CIF service;
3. >500kg, sea shipping recommended, usually called FOB, CFR, or CIF service;
4. For high-value products, please select air shipping and express delivery for safe.
Quality Control of α-Naphthoflavone
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